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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for MXI1 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID4601
Official gene symbolMXI1
Full nameMAX interactor 1
Aliases,MAD2,MGC43220,MXD2,MXI,bHLHc11,
Gene summaryExpression of the c-myc gene, which produces an oncogenic transcription factor, is tightly regulated in normal cells but is frequently deregulated in human cancers. The protein encoded by this gene is a transcriptional repressor thought to negatively regulate MYC function, and is therefore a potential tumor suppressor. This protein inhibits the transcriptional activity of MYC by competing for MAX, another basic helix-loop-helix protein that binds to MYC and is required for its function. Defects in this gene are frequently found in patients with prostate tumors. Three alternatively spliced transcripts encoding different isoforms have been described. Additional alternatively spliced transcripts may exist but the products of these transcripts have not been verified experimentally. [provided by RefSeq]
LocationChromosome: 10   Locus: 10q24-q25
Gene position111967363 - 112047123  Map Viewer
Gene orientationplus
Gene size79761 bp
Gene sequence
OMIM ID600020