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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for MYC (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 4609 Official gene symbol MYC Full name v-myc myelocytomatosis viral oncogene homolog (avian) Aliases ,MRTL,bHLHe39,c-Myc, Gene summary The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene. [provided by RefSeq] Location Chromosome: 8   Locus: 8q24.21 Gene position 128748315 - 128753680  Map Viewer Gene orientation plus Gene size 5366 bp Gene sequence >MYC:42021864..42027229:Length=5366 GACCCCCGAGCTGTGCTGCTCGCGGCCGCCACCGCCGGGCCCCGGCCGTCCCTGGCTCCC CTCCTGCCTCGAGAAGGGCAGGGCTTCTCAGAGGCTTGGCGGGAAAAAGAACGGAGGGAG GGATCGCGCTGAGTATAAAAGCCGGTTTTCGGGGCTTTATCTAACTCGCTGTAGTAATTC CAGCGAGAGGCAGAGGGAGCGAGCGGGCGGCCGGCTAGGGTGGAAGAGCCGGGCGAGCAG AGCTGCGCTGCGGGCGTCCTGGGAAGGGAGATCCGGAGCGAATAGGGGGCTTCGCCTCTG GCCCAGCCCTCCCGCTGATCCCCCAGCCAGCGGTCCGCAACCCTTGCCGCATCCACGAAA CTTTGCCCATAGCAGCGGGCGGGCACTTTGCACTGGAACTTACAACACCCGAGCAAGGAC GCGACTCTCCCGACGCGGGGAGGCTATTCTGCCCATTTGGGGACACTTCCCCGCCGCTGC CAGGACCCGCTTCTCTGAAAGGCTCTCCTTGCAGCTGCTTAGACGCTGGATTTTTTTCGG GTAGTGGAAAACCAGGTAAGCACCGAAGTCCACTTGCCTTTTAATTTATTTTTTTATCAC TTTAATGCTGAGATGAGTCGAATGCCTAAATAGGGTGTCTTTTCTCCCATTCCTGCGCTA TTGACACTTTTCTCAGAGTAGTTATGGTAACTGGGGCTGGGGTGGGGGGTAATCCAGAAC TGGATCGGGGTAAAGTGACTTGTCAAGATGGGAGAGGAGAAGGCAGAGGGAAAACGGGAA TGGTTTTTAAGACTACCCTTTCGAGATTTCTGCCTTATGAATATATTCACGCTGACTCCC GGCCGGTCGGACATTCCTGCTTTATTGTGTTAATTGCTCTCTGGGTTTTGGGGGGCTGGG GGTTGCTTTGCGGTGGGCAGAAAGCCCCTTGCATCCTGAGCTCCTTGGAGTAGGGACCGC ATATCGCCTGTGTGAGCCAGATCGCTCCGCAGCCGCTGACTTGTCCCCGTCTCCGGGAGG GCATTTAAATTTCGGCTCACCGCATTTCTGACAGCCGGAGACGGACACTGCGGCGCGTCC CGCCCGCCTGTCCCCGCGGCGATTCCAACCCGCCCTGATCCTTTTAAGAAGTTGGCATTT GGCTTTTTAAAAAGCAATAATACAATTTAAAACCTGGGTCTCTAGAGGTGTTAGGACGTG GTGTTGGGTAGGCGCAGGCAGGGGAAAAGGGAGGCGAGGATGTGTCCGATTCTCCTGGAA TCGTTGACTTGGAAAAACCAGGGCGAATCTCCGCACCCAGCCCTGACTCCCCTGCCGCGG CCGCCCTCGGGTGTCCTCGCGCCCGAGATGCGGAGGAACTGCGAGGAGCGGGGCTCTGGG CGGTTCCAGAACAGCTGCTACCCTTGGTGGGGTGGCTCCGGGGGAGGTATCGCAGCGGGG TCTCTGGCGCAGTTGCATCTCCGTATTGAGTGCGAAGGGAGGTGCCCCTATTATTATTTG ACACCCCCCTTGTATTTATGGAGGGGTGTTAAAGCCCGCGGCTGAGCTCGCCACTCCAGC CGGCGAGAGAAAGAAGAAAAGCTGGCAAAAGGAGTGTTGGACGGGGGCGGTACTGGGGGT GGGGACGGGGGCGGTGGAGAGGGAAGGTTGGGAGGGGCTGCGGTGCCGGCGGGGGTAGGA GAGCGGCTAGGGCGCGAGTGGGAACAGCCGCAGCGGAGGGGCCCCGGCGCGGAGCGGGGT TCACGCAGCCGCTAGCGCCCAGGCGCCTCTCGCCTTCTCCTTCAGGTGGCGCAAAACTTT GTGCCTTGGATTTTGGCAAATTGTTTTCCTCACCGCCACCTCCCGCGGCTTCTTAAGGGC GCCAGGGCCGATTTCGATTCCTCTGCCGCTGCGGGGCCGACTCCCGGGCTTTGCGCTCCG GGCTCCCGGGGGAGCGGGGGCTCGGCGGGCACCAAGCCGCTGGTTCACTAAGTGCGTCTC CGAGATAGCAGGGGACTGTCCAAAGGGGGTGAAAGGGTGCTCCCTTTATTCCCCCACCAA GACCACCCAGCCGCTTTAGGGGATAGCTCTGCAAGGGGAGAGGTTCGGGACTGTGGCGCG CACTGCGCGCTGCGCCAGGTTTCCGCACCAAGACCCCTTTAACTCAAGACTGCCTCCCGC TTTGTGTGCCCCGCTCCAGCAGCCTCCCGCGACGATGCCCCTCAACGTTAGCTTCACCAA CAGGAACTATGACCTCGACTACGACTCGGTGCAGCCGTATTTCTACTGCGACGAGGAGGA GAACTTCTACCAGCAGCAGCAGCAGAGCGAGCTGCAGCCCCCGGCGCCCAGCGAGGATAT CTGGAAGAAATTCGAGCTGCTGCCCACCCCGCCCCTGTCCCCTAGCCGCCGCTCCGGGCT CTGCTCGCCCTCCTACGTTGCGGTCACACCCTTCTCCCTTCGGGGAGACAACGACGGCGG TGGCGGGAGCTTCTCCACGGCCGACCAGCTGGAGATGGTGACCGAGCTGCTGGGAGGAGA CATGGTGAACCAGAGTTTCATCTGCGACCCGGACGACGAGACCTTCATCAAAAACATCAT CATCCAGGACTGTATGTGGAGCGGCTTCTCGGCCGCCGCCAAGCTCGTCTCAGAGAAGCT GGCCTCCTACCAGGCTGCGCGCAAAGACAGCGGCAGCCCGAACCCCGCCCGCGGCCACAG CGTCTGCTCCACCTCCAGCTTGTACCTGCAGGATCTGAGCGCCGCCGCCTCAGAGTGCAT CGACCCCTCGGTGGTCTTCCCCTACCCTCTCAACGACAGCAGCTCGCCCAAGTCCTGCGC CTCGCAAGACTCCAGCGCCTTCTCTCCGTCCTCGGATTCTCTGCTCTCCTCGACGGAGTC CTCCCCGCAGGGCAGCCCCGAGCCCCTGGTGCTCCATGAGGAGACACCGCCCACCACCAG CAGCGACTCTGGTAAGCGAAGCCCGCCCAGGCCTGTCAAAAGTGGGCGGCTGGATACCTT TCCCATTTTCATTGGCAGCTTATTTAACGGGCCACTCTTATTAGGAAGGAGAGATAGCAG ATCTGGAGAGATTTGGGAGCTCATCACCTCTGAAACCTTGGGCTTTAGCGTTTCCTCCCA TCCCTTCCCCTTAGACTGCCCATGTTTGCAGCCCCCCTCCCCGTTTGTCTCCCACCCCTC AGGAATTTCATTTAGGTTTTTAAACCTTCTGGCTTATCTTACAACTCAATCCACTTCTTC TTACCTCCCGTTAACATTTTAATTGCCCTGGGGCGGGGTGGCAGGGAGTGTATGAATGAG GATAAGAGAGGATTGATCTCTGAGAGTGAATGAATTGCTTCCCTCTTAACTTCCGAGAAG TGGTGGGATTTAATGAACTATCTACAAAAATGAGGGGCTGTGTTTAGAGGCTAGGCAGGG CCTGCCTGAGTGCGGGAGCCAGTGAACTGCCTCAAGAGTGGGTGGGCTGAGGAGCTGGGA TCTTCTCAGCCTATTTTGAACACTGAAAAGCAAATCCTTGCCAAAGTTGGACTTTTTTTT TTCTTTTATTCCTTCCCCCGCCCTCTTGGACTTTTGGCAAAACTGCAATTTTTTTTTTTT TATTTTTCATTTCCAGTAAAATAGGGAGTTGCTAAAGTCATACCAAGCAATTTGCAGCTA TCATTTGCAACACCTGAAGTGTTCTTGGTAAAGTCCCTCAAAAATAGGAGGTGCTTGGGA ATGTGCTTTGCTTTGGGTGTGTCCAAAGCCTCATTAAGTCTTAGGTAAGAATTGGCATCA ATGTCCTATCCTGGGAAGTTGCACTTTTCTTGTCCATGCCATAACCCAGCTGTCTTTCCC TTTATGAGACTCTTACCTTCATGGTGAGAGGAGTAAGGGTGGCTGGCTAGATTGGTTCTT TTTTTTTTTTTTTCCTTTTTTAAGACGGAGTCTCACTCTGTCACTAGGCTGGAGTGCAGT GGCGCAATCAACCTCCAACCCCCTGGTTCAAGAGATTCTCCTGCCTCAGCCTCCCAAGTA GCTGGGACTACAGGTGCACACCACCATGCCAGGCTAATTTTTGTAATTTTAGTAGAGATG GGGTTTCATCGTGTTGGCCAGGATGGTCTCTCCTGACCTCACGATCCGCCCACCTCGGCC TCCCAAAGTGCTGGGATTACAGGTGTGAGCCAGGGCACCAGGCTTAGATGTGGCTCTTTG GGGAGATAATTTTGTCCAGAGACCTTTCTAACGTATTCATGCCTTGTATTTGTACAGCAT TAATCTGGTAATTGATTATTTTAATGTAACCTTGCTAAAGGAGTGATTTCTATTTCCTTT CTTAAAGAGGAGGAACAAGAAGATGAGGAAGAAATCGATGTTGTTTCTGTGGAAAAGAGG CAGGCTCCTGGCAAAAGGTCAGAGTCTGGATCACCTTCTGCTGGAGGCCACAGCAAACCT CCTCACAGCCCACTGGTCCTCAAGAGGTGCCACGTCTCCACACATCAGCACAACTACGCA GCGCCTCCCTCCACTCGGAAGGACTATCCTGCTGCCAAGAGGGTCAAGTTGGACAGTGTC AGAGTCCTGAGACAGATCAGCAACAACCGAAAATGCACCAGCCCCAGGTCCTCGGACACC GAGGAGAATGTCAAGAGGCGAACACACAACGTCTTGGAGCGCCAGAGGAGGAACGAGCTA AAACGGAGCTTTTTTGCCCTGCGTGACCAGATCCCGGAGTTGGAAAACAATGAAAAGGCC CCCAAGGTAGTTATCCTTAAAAAAGCCACAGCATACATCCTGTCCGTCCAAGCAGAGGAG CAAAAGCTCATTTCTGAAGAGGACTTGTTGCGGAAACGACGAGAACAGTTGAAACACAAA CTTGAACAGCTACGGAACTCTTGTGCGTAAGGAAAAGTAAGGAAAACGATTCCTTCTAAC AGAAATGTCCTGAGCAATCACCTATGAACTTGTTTCAAATGCATGATCAAATGCAACCTC ACAACCTTGGCTGAGTCTTGAGACTGAAAGATTTAGCCATAATGTAAACTGCCTCAAATT GGACTTTGGGCATAAAAGAACTTTTTTATGCTTACCATCTTTTTTTTTTCTTTAACAGAT TTGTATTTAAGAATTGTTTTTAAAAAATTTTAAGATTTACACAATGTTTCTCTGTAAATA TTGCCATTAAATGTAAATAACTTTAATAAAACGTTTATAGCAGTTACACAGAATTTCAAT CCTAGTATATAGTACCTAGTATTATAGGTACTATAAACCCTAATTTTTTTTATTTAAGTA CATTTTGCTTTTTAAAGTTGATTTTTTTCTATTGTTTTTAGAAAAAATAAAATAACTGGC AAATATATCATTGAGCCAAATCTTAA OMIM ID 190080