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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for GADD45B (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 4616 Official gene symbol GADD45B Full name growth arrest and DNA-damage-inducible, beta Aliases ,DKFZp566B133,GADD45BETA,MYD118, Gene summary This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The genes in this group respond to environmental stresses by mediating activation of the p38/JNK pathway. This activation is mediated via their proteins binding and activating MTK1/MEKK4 kinase, which is an upstream activator of both p38 and JNK MAPKs. The function of these genes or their protein products is involved in the regulation of growth and apoptosis. These genes are regulated by different mechanisms, but they are often coordinately expressed and can function cooperatively in inhibiting cell growth. [provided by RefSeq] Location Chromosome: 19   Locus: 19p13.3 Gene position 2476123 - 2478257  Map Viewer Gene orientation plus Gene size 2135 bp Gene sequence >GADD45B:2416123..2418257:Length=2135 TCAGATCGCCGAAGCGTCGGACTACCGTTGGTTTCCGCAACTTCCTGGATTATCCTCGCC AAGGACTTTGCAATATATTTTTCCGCCTTTTCTGGAAGGATTTCGCTGCTTCCCGAAGGT CTTGGACGAGCGCTCTAGCTCTGTGGGAAGGTTTTGGGCTCTCTGGCTCGGATTTTGCAA TTTCTCCCTGGGGACTGCCGTGGAGCCGCATCCACTGTGGATTATAATTGCAACATGACG CTGGAAGAGCTCGTGGCGTGCGACAACGCGGCGCAGAAGTAAGTAGCCGGGGCTGCCGCC GCCTGAGGTCAGCCGGGACGGGATGGGTCGGGTTGGGCCGGGCCGGGAGCGGAACGTAGC ACCCGGTGGTCCGCCCGTCACTGATCCCTCTTTCCTGGTCTCAGGATGCAGACGGTGACC GCCGCGGTGGAGGAGCTTTTGGTGGCCGCTCAGCGCCAGGATCGCCTCACAGTGGGGGTG TACGAGTCGGCCAAGTTGATGAATGTGTGAGTCAGACCCCCTTCCCGGGCTGGGCGCGGG TGGGACGGGACCTCCCCTCCGCTCTGGACGCTTTCCGCACGCTTGTCTTGCATGGAGCTG GGACTTCCCCAAGTGCCCCCCGCTGTGGATGCAGAGCTTCTCTGCCGTTTTGTGGATCGG GGGCTGCCGTATCCTGATGTATCGTCTGCAAACACCCCTCCCGCCGTGGGCCTGTCTCCC CCTACCCCATACTTTGAACCGTGTGCCCTCCCCTCCCCCCACCGTCACCAGCTTGCAGAG GCAATCCCCTGCACCCTTGCAGTTTCTCTTTTGCTCTTGCACGCTCCTTTTTTGCAAACT CCCCCTGCACGGTGGCCCCTCCCCTGTCCCCGGCTGACCCATCCCTACCCTTTGGCCCCC TCAGGGACCCAGACAGCGTGGTCCTCTGCCTCTTGGCCATTGACGAGGAGGAGGAGGATG ACATCGCCCTGCAAATCCACTTCACGCTCATCCAGTCCTTCTGCTGTGACAACGACATCA ACATCGTGCGGGTGTCGGGCATGCAGCGCCTGGCGCAGCTCCTGGGAGAGCCGGCCGAGA CCCAGGGCACCACCGAGGCCCGAGACCTGCATTGTCTCCTGGTCACGGTGAGTCGGGCCT CTGCCCTGCCCCGCCACGCCCGGGCACCTGGGCCGGTGTTTGTCAACAAAGTCGGGCTGA CTGGTCCTGCACAGCTCAGCGCTCAGCCACGTTTGGCATGTCCCGTGGGCAGCCGGGCTG GGGCCTCCTCACCCAGGAAGCTATTTTGAGCCTGACTGTTTTCCCCACACAGGGGCCCCG GGAGAGGGAGGCTCCACTAAACCCCTTCTTTTCCCTCCTACAGAACCCTCACACGGACGC CTGGAAGAGCCACGGCTTGGTGGAGGTGGCCAGCTACTGCGAAGAAAGCCGGGGCAACAA CCAGTGGGTCCCCTACATCTCTCTTCAGGAACGCTGAGGCCCTTCCCAGCAGCAGAATCT GTTGAGTTGCTGCCACAAACAAAAAATACAATAAATATTTGAACCCCCTCCCCCCCAGCA CAACCCCCCCAAAACAACCCAACCCACGAGGACCATCGGGGGCAGAGTCGTTGGAGACTG AAGAGGAAGAGGAGGAGGAGAAGGGGAGTGAGCGGCCGCCCCCAGGGCGGAGATCCAGGA GCTGGCGGCCGCCGATCCGATGGAGAAGGGGGGACCCAGGCCAGCAGGAGACAGGACCCC CGAAGCTGAGGCCTTGGGATGGAGCAGAAGCCGGAGTGGCGGGGCACGCTGCCGCCTTCC CCATCACGGAGGGTCCAGACTGTCCACTCGGGGGTGGAGTGAGACTGACTGCAAGCCCCA CCCTCCTTGAGACTGGAGCTGGCGTCTGCATACGAGAGACTTGGTTGAACTTGGTTGGTC CTTGTCTGCACCCTCGACAAGACCACACTTTGGGACTTGGGAGCTGGGGCTGAAGTTGCT CTGTACCCATGAACTCCCAGTTTGCGAATTATAGAGACAATCTATTTTGTTACTTGCACT TGTTATTCGAACCACTGAGAGCGAGATGGGAAGCATAGATATCTATATTTTTATTTCTAC TATGAGGGCCTTGTAATAAATTTCTAAAGCCTCTG OMIM ID 604948