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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for MYH7 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID4625
Official gene symbolMYH7
Full namemyosin, heavy chain 7, cardiac muscle, beta
Aliases,CMD1S,CMH1,DKFZp451F047,MGC138376,MGC138378,MPD1,MYHCB,SPMD,SPMM,
Gene summaryMuscle myosin is a hexameric protein containing 2 heavy chain subunits, 2 alkali light chain subunits, and 2 regulatory light chain subunits. This gene encodes the beta (or slow) heavy chain subunit of cardiac myosin. It is expressed predominantly in normal human ventricle. It is also expressed in skeletal muscle tissues rich in slow-twitch type I muscle fibers. Changes in the relative abundance of this protein and the alpha (or fast) heavy subunit of cardiac myosin correlate with the contractile velocity of cardiac muscle. Its expression is also altered during thyroid hormone depletion and hemodynamic overloading. Mutations in this gene are associated with familial hypertrophic cardiomyopathy, myosin storage myopathy, dilated cardiomyopathy, and Laing early-onset distal myopathy. [provided by RefSeq]
LocationChromosome: 14   Locus: 14q12
Gene position23904870 - 23881947  Map Viewer
Gene orientationminus
Gene size22924 bp
Gene sequence
OMIM ID160760