Database of mammalian genes
Home

Home Search Browse Statistics User guide FAQs Links Questions Contribute Download


Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for ATF3 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID467
Official gene symbolATF3
Full nameactivating transcription factor 3
Aliases,-,
Gene summaryActivating transcription factor 3 is a member of the mammalian activation transcription factor/cAMP responsive element-binding (CREB) protein family of transcription factors. Multiple transcript variants encoding two different isoforms have been found for this gene. The longer isoform represses rather than activates transcription from promoters with ATF binding elements. The shorter isoform (deltaZip2) lacks the leucine zipper protein-dimerization motif and does not bind to DNA, and it stimulates transcription presumably by sequestering inhibitory co-factors away from the promoter. It is possible that alternative splicing of the ATF3 gene may be physiologically important in the regulation of target genes. [provided by RefSeq]
LocationChromosome: 1   Locus: 1q32.3
Gene position212738697 - 212794117  Map Viewer
Gene orientationplus
Gene size55421 bp
Gene sequence