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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for NDUFS4 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID4724
Official gene symbolNDUFS4
Full nameNADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase)
Aliases,AQDQ,CI-18,
Gene summaryThis gene encodes an accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), or NADH:ubiquinone oxidoreductase, the first multi-subunit enzyme complex of the mitochondrial respiratory chain. Complex I plays a vital role in cellular ATP production, the primary source of energy for many crucial processes in living cells. It removes electrons from NADH and passes them by a series of different protein-coupled redox centers to the electron acceptor ubiquinone. In well-coupled mitochondria, the electron flux leads to ATP generation via the building of a proton gradient across the inner membrane. Complex I is composed of at least 41 subunits, of which 7 are encoded by the mitochondrial genome and the remainder by nuclear genes. [provided by RefSeq]
LocationChromosome: 5   Locus: 5q11.1
Gene position52856465 - 52979171  Map Viewer
Gene orientationplus
Gene size122707 bp
Gene sequence
OMIM ID602694