Entrez gene ID | | 475 |
Official gene symbol | | ATOX1 |
Full name | | ATX1 antioxidant protein 1 homolog (yeast) |
Aliases | | ,ATX1,HAH1,MGC138453,MGC138455, |
Gene summary | | This gene encodes a copper chaperone that plays a role in copper homeostasis by binding and transporting cytosolic copper to ATPase proteins in the trans-Golgi network for later incorporation to the ceruloplasmin. This protein also functions as an antioxidant against superoxide and hydrogen peroxide, and therefore, may play a significant role in cancer carcinogenesis. Because of its cytogenetic location, this gene represents a candidate gene for 5q-syndrome. [provided by RefSeq] |
Location | | Chromosome: 5 Locus: 5q32 |
Gene position | | 151138210 - 151122383 Map Viewer |
Gene orientation | | minus |
Gene size | | 15828 bp |
Gene sequence |
| |
OMIM ID | | 602270 |