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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for NEU1 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 4758 Official gene symbol NEU1 Full name sialidase 1 (lysosomal sialidase) Aliases ,FLJ93471,NANH,NEU,SIAL1, Gene summary The protein encoded by this gene is a lysosomal enzyme that cleaves terminal sialic acid residues from substrates such as glycoproteins and glycolipids. In the lysosome, this enzyme is part of a heterotrimeric complex together with beta-galactosidase and cathepsin A (the latter is also referred to as 'protective protein'). Mutations in this gene can lead to sialidosis, a lysosomal storage disease that can be type 1 (cherry red spot-myoclonus syndrome or normosomatic type), which is late-onset, or type 2 (the dysmorphic type), which occurs at an earlier age with increased severity. [provided by RefSeq] Location Chromosome: 6   Locus: 6p21.3 Gene position 31830709 - 31826829  Map Viewer Gene orientation minus Gene size 3881 bp Gene sequence >NEU1:complement(3336576..3340456):Length=3881 GAGCTACTTGAAGACCAATTAGAGTCCGGGAAGCGCGGCGGGGCCTCCAGACCGGGGCGG GCTTAAGGGTGACATCTGCGCTTTAAAGGGTCCGGGTCAGCTGACTCCCGACTCTGTGGA GTCTAGCTGCCAGGGTCGCGGCAGCTGCGGGGAGAGATGACTGGGGAGCGACCCAGCACG GCGCTCCCGGACAGACGCTGGGGGCCGCGGATTCTGGGCTTCTGGGGAGGCTGTAGGGTT TGGGTGTTTGCCGCGATCTTCCTGCTGCTGTCTCTGGCAGCCTCCTGGTCCAAGGCTGAG AACGACTTCGGTCTGGTGAGTCACCCTTTGCATAGCCCCATCCCCGACCCGCGCAGGTGA TCGACACCTAGTGTCCCCCGGAACGCGGGCGGCTGAGCCGACTTTCCGCGACAGGACCCT TTTCTTTCTCCCAGACCCCGTTTCCTCCTACCGCTCCCAGCCCCTCTCCCTCTCCGGGTC CCCGTCCTTCTCCTCATTCGAGCCCCTTCCTCTTTTGGGGTCCCCTTCCCTCCCTGAAGG CGCCTTCTCCTTTCGTAGACCCTCCCCTGCTCCGAGCCTCCAGCTTCGCTCCAAACTCCC CTTCGTGTTCCTCTTTCTTGTTCTGGGACCCCATCCCCTACTCGGGATCCCCATTAGATC CTCCCTCTCCCATCGGAACGTGGGTTCCTAAAACCCCCAAGACAAGTTTGTCTTTGTTGA CCCTTCCTCCTCCCATGACAGGTGCAGCCGCTGGTGACCATGGAGCAACTGCTGTGGGTG AGCGGGAGACAGATCGGCTCAGTGGACACCTTCCGCATCCCGCTCATCACAGCCACTCCG CGGGGCACTCTTCTCGCCTTTGCTGAGGCGAGGAAAATGTCCTCATCCGATGAGGGGGCC AAGTTCATCGCCCTGCGGAGGTCCATGGACCAGGGTATAAAGATGTCTGGGTGAAAGAGC CGGTGCTAGGTTGGATGGGTGGGCAGCCCAATGAGCCCAAGGGCCCTGAGGATAGGGGAA CTTAGAGGGTTGGTTGCCTGAGTCCCTGAGGGGTAGAGGGAACCCGAGAAGGGCAAGTGT CTAGGACAGTGATCTGGAAATTGGGATCACCAAGGAGTTGGACATTCACTTAGCAAACAT TTATTGGGTACTATATACCTATACCAGGCACTATTTTAGGTTTCATGAATATAGCCACGA ACAAAACAGATCAAAAATCTCTGCCCTCAGGATTTAAATTGTACTGGAAGGAGACAGACA AGCATAATAAACAAGTAAACTTTTTTGTCTGTTGCAAGGTGATAAATGCAATGGAGAAAA ATAAAACAGGACAAGAGGTATAGATAGTGCAAGTGTTGGATTGCACCCTGGGACCATCGG AAGGCCTGAGGTCCCTAGCAGAAGGTGGGAAATTAACGGGAAGTGGTAGAAAGGGTACCT GCAGAGTGCTCACTCTGGGTTTCTTCCTCCAATTTTTTTCAGGCAGCACATGGTCTCCTA CAGCGTTCATTGTCAATGATGGGGATGTCCCCGATGGGCTGAACCTTGGGGCAGTAGTGA GCGATGTTGAGACAGGAGTAGTATTTCTTTTCTACTCCCTTTGTGCTCACAAGGCCGGCT GCCAGGTGGCCTCTACCATGTTGGTATGGAGCAAGGATGATGGTGTTTCCTGGAGCACAC CCCGGAATCTCTCCCTGGATATTGGCACTGAAGTGTTTGCCCCTGGACCGGGCTCTGGTA TTCAGGTCTCTGTCCTAGGAGATAGGTGGAGGGGGCTGCCTTGTGGAGAGTCTGAGGGAT ACCCCCAAATGGACTCCTTTCCAAGGGGAAGATTCTCTGAAGTCAGATTTTCTGGCTTGG GTGGGATTCCTTGAAAGACAGGGCATCCTGGTAGGAACACATTATCAGGAGAAGAGGGAA CTCTGCCATTGGCTTCCCATTTGGCATTGTCAACAGGACTGCGTTAGTCCATGCAATACC CTCATGCAAAGTAGAAAAAGGCACTGCCTCTTTGGACAGACACAAGCCTGTGCCAGGGTG CACAGCTTGGCGAGTGAGCACAGGTTGGGTTTAAGCTCTCATGCACCCTGTGGCTGGGCC CCTGGTGCACATGTCCAGCTGTACACCCTGGGAGAGCTTCTTAATTCAAACAGGGTGTGT ATTTATGGGATCTGACTGGAACCCTCAGTGAGCAAGGGCTGAACTCAAGGGGACCATACA TGTGATTGCATTTGGGAAGTGGTGGGTTCTCTGTCCCTGCCTCTGAGCCCCTAGAGTCTC CTTCTGTGACACCCAGTTCCCTTTCCCACAGAAACAGCGGGAGCCACGGAAGGGCCGCCT CATCGTGTGTGGCCATGGGACGCTGGAGCGGGACGGAGTCTTCTGTCTCCTCAGCGATGA TCATGGTGCCTCCTGGCGCTACGGAAGTGGGGTCAGCGGCATCCCCTACGGTCAGCCCAA GCAGGAAAATGATTTCAATCCTGATGAATGCCAGGTCAGGAGTCCATGAGATGTTCCCTA CCCATTTGACCCTCCCTGCCCTCCAGAACATCATTTCACGCACAGACCCAGGGTCTGACT GCTCCACTCAGTGCCACACACCCTTGCTCCCCTCGGGGACAGGGCATTTTCCCTGTTCCC TCCCTGAGGTCCTGTCCTCTCCCCTCAGCCCTATGAGCTCCCAGATGGCTCAGTCGTCAT CAATGCCCGAAACCAGAACAACTACCACTGCCACTGCCGAATTGTCCTCCGCAGCTATGA TGCCTGTGATACACTAAGGCCCCGTGATGTGACCTTCGACCCTGAGCTCGTGGACCCTGT GGTAGCTGCAGGAGCTGTAGTCACCAGCTCCGGCATTGTCTTCTTCTCCAACCCAGCACA TCCAGAGTTCCGTGAGTGCCTCATGGGTGGGGTCAGCAGGGAGAGCCCTGTGTCTAGACA AGGCCTGGGCAGAGACCCTCTCTCCCTGACTCTCCTGCTCTCCCCAGGAGTGAACCTGAC CCTGCGATGGAGCTTCAGCAATGGTACCTCATGGCGGAAAGAGACAGTCCAGCTATGGCC AGGCCCCAGTGGCTATTCATCCCTGGCAACCCTGGAGGGCAGCATGGATGGAGAGGAGCA GGCCCCCCAGCTCTACGTCCTGTATGAGAAAGGCCGGAACCACTACACAGAGAGCATCTC CGTGGCCAAAATCAGTGTCTATGGGACACTCTGAGCTGTGCCACTGCCACAGGGGTATTC TGCCTTCAGGACTCTGCCTTCAGGAACACAGGTCTGTAGAGGGTCTGCTGGAGACGCCTG AAAGACAGTTCCATCTTCCTTTAGACTCCAGCCTTGGCAAAATCACCTTCCCTTTACCAG GGAAATCACTTCCTTTAGGACTGAAAGCTAGGCGTCCTCTCCCACAAAAAAGTCCTGCCC TCATCTGAGAATACTGTCTTTCCATATGGCTAAGTGTGGCCCCACCACCCTCTCTGCCCT CCCGGGACATTGATTGGTCCTGTCTTGGGCAGGTCTAGTGAGCTGTAGAATTGAATCAAT GTGAACTCAGGGAACTGGGGAAGGCTGAGCCTCCTCTTTGGTGTTGCGGTAAGATAACCG ACAGGGCTGGTGAAAGTCCCCAGATGGCAGGATATTTGGTTTCAGAGTAAGGACTAGGTG CACCACCATGACTGACTATCAATCAAAATGTTTGTAACTTAAAATTTTTAATGAAGGATA ATGAATATTTGTAGAGTCTCTATGGTTCTGTCAATGCACATCTTCGTGTCTGTTTTCCTC ATGTATCCTTGTGAGCCTGGGTGAGTTCTGGGGAGAGACCTGATGTGCGTACTGCCTGTG AAAATCTGACTTTGGCAAATCAAATCCTCTTTTCCTTTTGA OMIM ID 608272