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Gene information for ATP1A2 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID477
Official gene symbolATP1A2
Full nameATPase, Na+/K+ transporting, alpha 2 polypeptide
Aliases,FHM2,MGC59864,MHP2,
Gene summaryThe protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an alpha 2 subunit. Mutations in this gene result in familial basilar or hemiplegic migraines, and in a rare syndrome known as alternating hemiplegia of childhood. [provided by RefSeq]
LocationChromosome: 1   Locus: 1q21-q23
Gene position160085520 - 160113381  Map Viewer
Gene orientationplus
Gene size27862 bp
Gene sequence
OMIM ID182340