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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for ATP1B1 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID481
Official gene symbolATP1B1
Full nameATPase, Na+/K+ transporting, beta 1 polypeptide
Aliases,ATP1B,MGC1798,
Gene summaryThe protein encoded by this gene belongs to the family of Na+/K+ and H+/K+ ATPases beta chain proteins, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane. The glycoprotein subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes a beta 1 subunit. Alternatively spliced transcript variants encoding different isoforms have been described, but their biological validity is not known. [provided by RefSeq]
LocationChromosome: 1   Locus: 1q24
Gene position169075947 - 169101960  Map Viewer
Gene orientationplus
Gene size26014 bp
Gene sequence
OMIM ID182330