Database of mammalian genes
Home

Home Search Browse Statistics User guide FAQs Links Questions Contribute Download


Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for NPY (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID4852
Official gene symbolNPY
Full nameneuropeptide Y
Aliases,PYY4,
Gene summaryThis gene encodes a neuropeptide that is widely expressed in the central nervous system and influences many physiological processes, including cortical excitability, stress response, food intake, circadian rhythms, and cardiovascular function. The neuropeptide functions through G protein-coupled receptors to inhibit adenylyl cyclase, activate mitogen-activated protein kinase (MAPK), regulate intracellular calcium levels, and activate potassium channels. A polymorphism in this gene resulting in a change of leucine 7 to proline in the signal peptide is associated with elevated cholesterol levels, higher alcohol consumption, and may be a risk factor for various metabolic and cardiovascular diseases. [provided by RefSeq]
LocationChromosome: 7   Locus: 7p15.1
Gene position24323807 - 24331484  Map Viewer
Gene orientationplus
Gene size7678 bp
Gene sequence
OMIM ID162640