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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for ATP2A1 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID487
Official gene symbolATP2A1
Full nameATPase, Ca++ transporting, cardiac muscle, fast twitch 1
Aliases,ATP2A,SERCA1,
Gene summaryThis gene encodes one of the SERCA Ca(2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen, and is involved in muscular excitation and contraction. Mutations in this gene cause some autosomal recessive forms of Brody disease, characterized by increasing impairment of muscular relaxation during exercise. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq]
LocationChromosome: 16   Locus: 16p12.1
Gene position28889809 - 28915830  Map Viewer
Gene orientationplus
Gene size26022 bp
Gene sequence
OMIM ID108730