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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for NPTX2 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID4885
Official gene symbolNPTX2
Full nameneuronal pentraxin II
Aliases,NARP,NP-II,NP2,
Gene summaryThis gene encodes a member of the family of neuronal petraxins, synaptic proteins that are related to C-reactive protein. This protein is involved in excitatory synapse formation. It also plays a role in clustering of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)-type glutamate receptors at established synapses, resulting in non-apoptotic cell death of dopaminergic nerve cells. Up-regulation of this gene in Parkinson disease (PD) tissues suggests that the protein may be involved in the pathology of PD. [provided by RefSeq]
LocationChromosome: 7   Locus: 7q21.3-q22.1
Gene position98246597 - 98259181  Map Viewer
Gene orientationplus
Gene size12585 bp
Gene sequence
OMIM ID600750