Entrez gene ID | | 4885 |
Official gene symbol | | NPTX2 |
Full name | | neuronal pentraxin II |
Aliases | | ,NARP,NP-II,NP2, |
Gene summary | | This gene encodes a member of the family of neuronal petraxins, synaptic proteins that are related to C-reactive protein. This protein is involved in excitatory synapse formation. It also plays a role in clustering of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)-type glutamate receptors at established synapses, resulting in non-apoptotic cell death of dopaminergic nerve cells. Up-regulation of this gene in Parkinson disease (PD) tissues suggests that the protein may be involved in the pathology of PD. [provided by RefSeq] |
Location | | Chromosome: 7 Locus: 7q21.3-q22.1 |
Gene position | | 98246597 - 98259181 Map Viewer |
Gene orientation | | plus |
Gene size | | 12585 bp |
Gene sequence |
| |
OMIM ID | | 600750 |
|