| Entrez gene ID | | 49 |
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| Official gene symbol | | ACR |
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| Full name | | acrosin |
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| Aliases | | ,-, |
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| Gene summary | | Acrosin is the major proteinase present in the acrosome of mature spermatozoa. It is a typical serine proteinase with trypsin-like specificity. It is stored in the acrosome in its precursor form, proacrosin. The active enzyme functions in the lysis of the zona pellucida, thus facilitating penetration of the sperm through the innermost glycoprotein layers of the ovum. The mRNA for proacrosin is synthesized only in the postmeiotic stages of spermatogenesis. In humans proacrosin first appears in the haploid spermatids. [provided by RefSeq] |
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| Location | | Chromosome: 22 Locus: 22q13-qter|22q13.33 |
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| Gene position | | 51176652 - 51183727 Map Viewer |
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| Gene orientation | | plus |
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| Gene size | | 7076 bp |
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| Gene sequence |
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