Entrez gene ID | | 4916 |
Official gene symbol | | NTRK3 |
Full name | | neurotrophic tyrosine kinase, receptor, type 3 |
Aliases | | ,TRKC,gp145(trkC), |
Gene summary | | This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation and may play a role in the development of proprioceptive neurons that sense body position. Mutations in this gene have been associated with medulloblastomas, secretory breast carcinomas and other cancers. [provided by RefSeq] |
Location | | Chromosome: 15 Locus: 15q25 |
Gene position | | 88799661 - 88419988 Map Viewer |
Gene orientation | | minus |
Gene size | | 379674 bp |
Gene sequence |
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OMIM ID | | 191316 |
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