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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for OPRM1 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID4988
Official gene symbolOPRM1
Full nameopioid receptor, mu 1
Aliases,KIAA0403,LMOR,MOR,MOR1,OPRM,
Gene summaryThe OPRM1 gene encodes the mu opioid receptor, which is the primary site of action for the most commonly used opioids, including morphine, heroin, fentanyl, and methadone. It is also the primary receptor for endogenous opioid peptides beta-endorphin (see POMC, MIM 176830) and the enkephalins (see PENK, MIM 131330). The OPRM1 receptor is a membrane of the G protein-coupled receptor family (Bond et al., 1998 [PubMed 9689128]). There are at least 3 types of opioid receptors, mu, kappa (OPRK1; MIM 165196), and delta (OPRD1; MIM 165195), each with a distinct pharmacologic profile (Chen et al., 1993 [PubMed 8393525]).[supplied by OMIM]
LocationChromosome: 6   Locus: 6q24-q25
Gene position154331636 - 154568001  Map Viewer
Gene orientationplus
Gene size236366 bp
Gene sequence
OMIM ID600018