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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for ACO2 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID50
Official gene symbolACO2
Full nameaconitase 2, mitochondrial
Aliases,ACONM,MGC20605,MGC33908,
Gene summaryThe protein encoded by this gene belongs to the aconitase/IPM isomerase family. It is an enzyme that catalyzes the interconversion of citrate to isocitrate via cis-aconitate in the second step of the TCA cycle. This protein is encoded in the nucleus and functions in the mitochondrion. It was found to be one of the mitochondrial matrix proteins that are preferentially degraded by the serine protease 15(PRSS15), also known as Lon protease, after oxidative modification. [provided by RefSeq]
LocationChromosome: 22   Locus: 22q11.2-q13.31|22q13
Gene position41865129 - 41924993  Map Viewer
Gene orientationplus
Gene size59865 bp
Gene sequence
OMIM ID100850