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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for P2RX3 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID5024
Official gene symbolP2RX3
Full namepurinergic receptor P2X, ligand-gated ion channel, 3
Aliases,MGC129956,P2X3,
Gene summaryThe product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and may transduce ATP-evoked nociceptor activation. Mouse studies suggest that this receptor is important for peripheral pain responses, and also participates in pathways controlling urinary bladder volume reflexes. It is possible that the development of selective antagonists for this receptor may have a therapeutic potential in pain relief and in the treatment of disorders of urine storage. [provided by RefSeq]
LocationChromosome: 11   Locus: 11q12
Gene position57105949 - 57137549  Map Viewer
Gene orientationplus
Gene size31601 bp
Gene sequence
OMIM ID600843