Entrez gene ID | | 5024 |
Official gene symbol | | P2RX3 |
Full name | | purinergic receptor P2X, ligand-gated ion channel, 3 |
Aliases | | ,MGC129956,P2X3, |
Gene summary | | The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and may transduce ATP-evoked nociceptor activation. Mouse studies suggest that this receptor is important for peripheral pain responses, and also participates in pathways controlling urinary bladder volume reflexes. It is possible that the development of selective antagonists for this receptor may have a therapeutic potential in pain relief and in the treatment of disorders of urine storage. [provided by RefSeq] |
Location | | Chromosome: 11 Locus: 11q12 |
Gene position | | 57105949 - 57137549 Map Viewer |
Gene orientation | | plus |
Gene size | | 31601 bp |
Gene sequence |
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OMIM ID | | 600843 |
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