Database of mammalian genes
Home

Home Search Browse Statistics User guide FAQs Links Questions Contribute Download


Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for PA2G4 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID5036
Official gene symbolPA2G4
Full nameproliferation-associated 2G4, 38kDa
Aliases,EBP1,HG4-1,p38-2G4,
Gene summaryThis gene encodes an RNA-binding protein that is involved in growth regulation. This protein is present in pre-ribosomal ribonucleoprotein complexes and may be involved in ribosome assembly and the regulation of intermediate and late steps of rRNA processing. This protein can interact with the cytoplasmic domain of the ErbB3 receptor and may contribute to transducing growth regulatory signals. This protein is also a transcriptional co-repressor of androgen receptor-regulated genes and other cell cycle regulatory genes through its interactions with histone deacetylases. This protein has been implicated in growth inhibition and the induction of differentiation of human cancer cells. Six pseudogenes, located on chromosomes 3, 6, 9, 18, 20 and X, have been identified. [provided by RefSeq]
LocationChromosome: 12   Locus: 12q13.2
Gene position56498103 - 56507694  Map Viewer
Gene orientationplus
Gene size9592 bp
Gene sequence
OMIM ID602145