Entrez gene ID | | 50488 |
Official gene symbol | | MINK1 |
Full name | | misshapen-like kinase 1 (zebrafish) |
Aliases | | ,B55,MAP4K6,MGC21111,MINK,YSK2,ZC3,hMINK,hMINKbeta, |
Gene summary | | This gene encodes a serine/threonine kinase belonging to the germinal center kinase (GCK) family. The protein is structurally similar to the kinases that are related to NIK and may belong to a distinct subfamily of NIK-related kinases within the GCK family. Studies of the mouse homolog indicate an up-regulation of expression in the course of postnatal mouse cerebral development and activation of the cJun N-terminal kinase (JNK) and the p38 pathways. Alternative splicing occurs at this locus and four transcript variants encoding distinct isoforms have been identified. [provided by RefSeq] |
Location | | Chromosome: 17 Locus: 17p13.2 |
Gene position | | 4736635 - 4801356 Map Viewer |
Gene orientation | | plus |
Gene size | | 64722 bp |
Gene sequence |
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OMIM ID | | 609426 |