Entrez gene ID | | 5058 |
Official gene symbol | | PAK1 |
Full name | | p21 protein (Cdc42/Rac)-activated kinase 1 |
Aliases | | ,MGC130000,MGC130001,PAKalpha, |
Gene summary | | This gene encodes a family member of serine/threonine p21-activating kinases, known as PAK proteins. These proteins are critical effectors that link RhoGTPases to cytoskeleton reorganization and nuclear signaling, and they serve as targets for the small GTP binding proteins Cdc42 and Rac. This specific family member regulates cell motility and morphology. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq] |
Location | | Chromosome: 11 Locus: 11q13-q14 |
Gene position | | 77185108 - 77033060 Map Viewer |
Gene orientation | | minus |
Gene size | | 152049 bp |
Gene sequence |
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OMIM ID | | 602590 |