Entrez gene ID | | 5066 |
Official gene symbol | | PAM |
Full name | | peptidylglycine alpha-amidating monooxygenase |
Aliases | | ,PAL,PHM, |
Gene summary | | This gene encodes a multifunctional protein. It has two enzymatically active domains with catalytic activities - peptidylglycine alpha-hydroxylating monooxygenase (PHM) and peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL). These catalytic domains work sequentially to catalyze neuroendocrine peptides to active alpha-amidated products. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene but some of their full length sequences are not yet known. [provided by RefSeq] |
Location | | Chromosome: 5 Locus: 5q14-q21 |
Gene position | | 102201527 - 102366809 Map Viewer |
Gene orientation | | plus |
Gene size | | 165283 bp |
Gene sequence |
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OMIM ID | | 170270 |