Entrez gene ID | | 5069 |
Official gene symbol | | PAPPA |
Full name | | pregnancy-associated plasma protein A, pappalysin 1 |
Aliases | | ,ASBABP2,DIPLA1,IGFBP-4ase,PAPA,PAPP-A,PAPPA1, |
Gene summary | | This gene encodes a secreted metalloproteinase which cleaves insulin-like growth factor binding proteins (IGFBPs). It is thought to be involved in local proliferative processes such as wound healing and bone remodeling. Low plasma level of this protein has been suggested as a biochemical marker for pregnancies with aneuploid fetuses. [provided by RefSeq] |
Location | | Chromosome: 9 Locus: 9q33.2 |
Gene position | | 118916071 - 119164600 Map Viewer |
Gene orientation | | plus |
Gene size | | 248530 bp |
Gene sequence |
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OMIM ID | | 176385 |