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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for DHH (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 50846 Official gene symbol DHH Full name desert hedgehog homolog (Drosophila) Aliases ,HHG-3,MGC35145, Gene summary This gene encodes a member of the hedgehog family. The hedgehog gene family encodes signaling molecules that play an important role in regulating morphogenesis. This protein is predicted to be made as a precursor that is autocatalytically cleaved; the N-terminal portion is soluble and contains the signalling activity while the C-terminal portion is involved in precursor processing. More importantly, the C-terminal product covalently attaches a cholesterol moiety to the N-terminal product, restricting the N-terminal product to the cell surface and preventing it from freely diffusing throughout the organism. Defects in this protein have been associated with partial gonadal dysgenesis (PGD) accompanied by minifascicular polyneuropathy. This protein may be involved in both male gonadal differentiation and perineurial development. [provided by RefSeq] Location Chromosome: 12   Locus: 12q12-q13.1 Gene position 49488602 - 49483204  Map Viewer Gene orientation minus Gene size 5399 bp Gene sequence >DHH:complement(11626510..11631908):Length=5399 GTCCGGAGTCCGGGCGTTCTGGCAGCACCAGAGTCCTGCAGCAGAGACGGGCTGGGCTGG CACTCACCCACGACCCCCCTTCCCTGCTATGATGGTTTGTCAGTAGCAGGTCCTAGACAC CCCCCGCCCGCTCCCGGGGCACGTGGGCAGAGCTAGCAGCAGCCAGGTGCACGGAGCCAC AAGAGCTCTAGGGCACTCTGGGGGCAGCTGTGCCTGCTGCCCTCTCTGGTGCCTGTGGAG ATGCCTAACTGACAGGAGAGTTAGTGAGGACAAGAACGCTCCCTTTTGGCCGAGGTCCGC TGTATCCATGGCTCTCCTGACCAATCTACTGCCCCTGTGCTGCTTGGCACTTCTGGCGCT GCCAGCCCAGAGCTGCGGGCCGGGCCGGGGGCCGGTTGGCCGGCGCCGCTATGCGCGCAA GCAGCTCGTGCCGCTACTCTACAAGCAATTTGTGCCCGGCGTGCCAGAGCGGACCCTGGG CGCCAGTGGGCCAGCGGAGGGGAGGGTGGCAAGGGGCTCCGAGCGCTTCCGGGACCTCGT GCCCAACTACAACCCCGACATCATCTTCAAGGATGAGGAGAACAGTGGAGCCGACCGCCT GATGACCGAGGTAAGGAGGGCCTCTCCCTACCTGCGCCGGGGCACTGCCAGCTCCTCCGT TTTCCTATGGCAGCCCAGGTGGGTGAGTCCAGCTTCACCTACAGAGAGTTTAGCCTTAGA GATTTCCCTTGTCACCAGCCCCAGGGGGGGGAAAAATCCTTGCAGTCTGGACAGAGTAAT TAGGACGGCTCCCGACTAGAATAGTCTGGGATGGGGAGGGGAGGAGGGACTGACTAGTGA GAGTGAAGCTGGTAGAGGCAGCGAGGGCGGGGAAAGGAGGATGGCGGCAGGCGAGACGGG AAATGGCTGAGGCGTGGACCGGGGGTCAGCCACCCAGCCAGGCAGGAAGGGCTGGGGTGA GCTGGGGGCCAGGAGCTGGCTAGGTAGCAGACAGAAGCCTGGCTCCTGACCTGATTGTAG AAAAGCTCTGTGGGCCGAAAAGAAGAGACTGAAAAGGGCTGGGACAGGGGTGGCCAAGGG TCAGGTCACCAGACCATCTACCTGAGGAGGGGCTGGGCAGACATTGCTTTTGGCATGGGA AACGTGTCCTAGAACCAGGACACATCTATTCTAGGGTCTATTCTAGGGCTATCCTAGGGT CTAAACGATAATCTTGGGGTTAAAAAGTAATCCTCAGTGAGAATAACAGATGGACCCACC TGAGAATCAGAGGGCTCCTAAGTCTTCCAAGCTCTGCCTATCTCAGGGGCTTTCCTTGGA ATTACATAATTAGGATAAATTCAACTACCATTTTTGAGCATTGGAACCACCTAGAGTGAG GTGGAAGAGAAGGACCACCTCTGGCGAGTGATTTATTTTTTATTTTTTGTAGAGACGGGG TCTTGCCATGTTGCCTAGGCTAGTCTTGAACTCCTGAGCTCAAGGGATCCTCCCACCTCG GCCTCCCAAAGTGCTGGATTACAGGTGTGAGCCACTTCATCCAGCCTGGCCAGTGATCTT GAATGTTAGAACTGAAAGAAAACTTGAGAGATGACATTCCTCCAACCCTCCCCACCCCCA CTGCCACCCTCATTTTACATCTGAGAGCTGGACTTCCCCCAGGAGGAAAAGCAATTTAAA CTCTCACAATTTAAAGTGGCATGGCTGGGACTAGAATTCAGGACTCCTGATTCTAAGCCC TATATACTTTCCATTACACCACCTAATTGTGTATGGAGTGGGGAGGTGGGGGGAGAGGGA GGGGTACGGATTTCCTCTGATTAATTGCCATAGTTTTCCAGGTTACTTTGTTAGGAAAAC CTGTCCAGGGAAGAAATAATTCCTTTTGCTTCTGCCCTGAAGCCTTCCTCCTACCTAGAG ATGGGAAAAGGGGCATTCCTTCTTTCCTCCTTGGCCGTGGAACATTGTGGCCCTTTCCTC TGGTTGCCACCTGCAGCAGAGTGGGCAGAACAAGGGACAGGCTCAGGAGGGGCTCCGGCA GGCCTGGGAGCCCCCTCAGTCTTACTTATCTCCCACACCCTGGCTGCAAAAGGCCTCCAT TGAGTTGGCTCTGCACTGGGCTGCTGCCCCCGCAGGTCAGGGCCTCGGGGCCTCCTTAGG GGACGAAACGACAAAGTTGGAAGGAGCTACCACTTTTCCTGTTTTCCCCCCACCCAACCC CAACTCTGCGGGGTGGAGGAGACTAGAGGAGAGGGGAAAAGTGTCTTTCTGTTAGGAGAA AACCAAGTCCGAGGTGAGAGGTCGGAGGGGAAAGAAAAAAAGGAAGCTGTCCCTCTGCGC CTCCTCCCGCGGTGTCCCTGCTATGGTGCGCGCCAAGGTCTCCCGCTCCCAGGCTGGAGC GGCCAAGATAACTGTGGTCTCACTCCCCCAGGTGCAGGCTTCCAGCCGCAGCTTCTTTTC CTCTTCTCCGCTCTCACCCTGCAGGGGGCTCCCCAGATCCGCACAAGGAGACCGTTATTC TCAGGTGCTACTCCCACGCCCTTCTGGGCTGCATCTAGAGCAGAGATGGGAGAGATAGGG GCTCTCCGGACTGGCAGAGCCTTAGCTGGAACTGGGAAGACTGGACGCGCGGGGGGAGGG GACCTACCCGGACGGAGCAGGGATTGGGGGCGCGGCTTTCTGCCCTTTCCTCTCCCTGAG CCGGGGCGGCTGAAAAGCGCCTTTGTGGCCGGAGCTGCTGAGTCCGCTTCTCCCAGCGCG TTCCCGGCCTGGGCTCAGGATTCTCGCTCGGTTAAGTCATCCCGGATAATGGCCATTGTA CTTCGCGCAACCCCCGCCACCCCAATCCTTTTTCCAGCAGCCTTGATCCCGCACAGCTCC TCTTGGGCACCTCTCTGGGGGGCACCCAGAGCACGAAGGGGTTAATGCTAAGGGCCCAAA GGAGGAGGAGGAAGGAAGGAAGGAAGCGATGCCCGGTGCCAGGGAAGGCAATGAAACAAA AGATGAATCAGGCGGAGGGAGGGGAGCCGGTGCCTGGGGCGGGGGCCAGGCTCAAACAGG GGCTCTCCGGGAGCAACCAGGCCCTCCCTGACCACGCTTCCATTCGCCCTCCTAACTCTG TCCTTCTCCCAGGTTGAGCCGCTGTCCCTGAACCAATAGGGGTGAGGGACGGGCATTAAA AATGGGGAAGGAGCTAGGTATGGGCACCCCCTCTCAACCTCAGAGGTGAGCCCACAGTTC TCCAACGACGTCCTGGGAACAGAGTGCAGATTGGTGACTACCATCGACTCAGATTCTCAT TTCTCCAGGACACTCAAAAGCTGGGAGGGGTAAGAGTAGGGCCGGAATAACAAAGAATCA ACCCTCCTATCCAGGTCCCTTTTGCCCCAAGGGTGGTGGTGGGGAGACTGACTCCTTTAT TCCCCGCCAGCGTTGTAAGGAGCGGGTGAACGCTTTGGCCATTGCCGTGATGAACATGTG GCCCGGAGTGCGCCTACGAGTGACTGAGGGCTGGGACGAGGACGGCCACCACGCTCAGGA TTCACTCCACTACGAAGGCCGTGCTTTGGACATCACTACGTCTGACCGCGACCGCAACAA GTATGGGTTGCTGGCGCGCCTCGCAGTGGAAGCCGGCTTCGACTGGGTCTACTACGAGTC CCGCAACCACGTCCACGTGTCGGTCAAAGCTGGTACAGTAGGAGGAGGGTGGTAAAATCC GCCCAAAGGGGGCTCCCTCCGGGAAACTGAGTCTGCAGTAGTACTGTTGCCACCCTAGGG GAGACCAAGCGGGCTTTAGTGTTGAAAACCACCCGTCCAGGCCGAGGCGGTGCCTCACGC CTCTAATCCCAGCACTTTGGGAGGCCAAGGAGGGCGGATCACTTGAGGTCAGGAGTTCGA GATCAGCCTAGCCAACATGGTGAAATCCCGTCTCTATTATAAATACGAAAATTAGTTGGG CGTGGTGGTGTATGCCTGTAATCCCGGCTACTCGTGAGGCTGAGGCACGAGAATCACTTG AACCCGGGAGGTAGAAGTTGCAGTGAGCCGAGATGGTGCCACTGCACTCCATCTACTGGG CGACAGAGCGAGATTCTATCTCAAAATACATACATACATACATACATACATACATACATA CATACATACATAGAAAAGAGAAGAAAAAGGAAAAGAAAAGAAAGAAAAACCGCCCTTCCT TTTCTGCCCAGGTTGGGGCCAGTCAGATTAACGGAAAATTGTGTTGTCCATGACTGGCGA TATCTGCGCTGGCCTTGAGAATCGTTCTGGAACCGCTGGTCTTGATTCAATCCTCCCTGT GGTTGTTCCCTGCAGATAACTCACTGGCGGTCCGGGCGGGCGGCTGCTTTCCGGGAAATG CAACTGTGCGCCTGTGGAGCGGCGAGCGGAAAGGGCTGCGGGAACTGCACCGCGGAGACT GGGTTTTGGCGGCCGATGCGTCAGGCCGGGTGGTGCCCACGCCGGTGCTGCTCTTCCTGG ACCGGGACTTGCAGCGCCGGGCTTCATTTGTGGCTGTGGAGACCGAGTGGCCTCCACGCA AACTGTTGCTCACGCCCTGGCACCTGGTGTTTGCCGCTCGAGGGCCGGCGCCCGCGCCAG GCGACTTTGCACCGGTGTTCGCGCGCCGGCTACGCGCTGGGGACTCGGTGCTGGCGCCCG GCGGGGATGCGCTTCGGCCAGCGCGCGTGGCCCGTGTGGCGCGGGAGGAAGCCGTGGGCG TGTTCGCGCCGCTCACCGCGCACGGGACGCTGCTGGTGAACGATGTCCTGGCCTCTTGCT ACGCGGTTCTGGAGAGTCACCAGTGGGCGCACCGCGCTTTTGCCCCCTTGAGACTGCTGC ACGCGCTAGGGGCGCTGCTCCCCGGCGGGGCCGTCCAGCCGACTGGCATGCATTGGTACT CTCGGCTCCTCTACCGCTTAGCGGAGGAGCTACTGGGCTGAGCGTCCCAGGCATAGAAAC CTCGAAGCGCCCGAGGAAACGAGGGCCTGCTGGCTGAGATATGGGGCTGTGGGCAGCAGA CGATGCCGACTGGAAGGGAGGGAGAGGGAGGGGGAGGGAGAAAATGGGGCTATGCCTGGC TTAGGGGCAACCTCGTACTGAGAGGAGGTGATACCGGGTCCTAGGTAGGTAGGGCTGATG GTGCGCACTCCTTAAAGAGGACTATTTAGCCTCTCCCCCAGTGCTTCAGCCCCACCCGAT AATTTTATTTTATTTCTTATTTATAAATTGTAATATAATGATTCCCTTGCCCAGCTTGCC AAGGTGAGGGGCTGGGGCATGGCATTAACACTGTCTGACACAGCCAGCCAGTCTGACATC TGACGTTTTCCTGCAAGGTGGGCTAATAAAGGGAAGGCTTTCAGGAGCTTACTGGAAAA OMIM ID 605423