| Entrez gene ID | | 5106 |
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| Official gene symbol | | PCK2 |
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| Full name | | phosphoenolpyruvate carboxykinase 2 (mitochondrial) |
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| Aliases | | ,PEPCK,PEPCK-M,PEPCK2, |
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| Gene summary | | This gene encodes a member of the phosphoenolpyruvate carboxykinase (GTP) family. The protein is a mitochondrial enzyme that catalyzes the conversion of oxaloacetate to phosphoenolpyruvate in the presence of GTP. A cytosolic form encoded by a different gene has also been characterized and is the key enzyme of gluconeogenesis in the liver. The encoded protein may serve a similar function, although it is constitutively expressed and not modulated by hormones such as glucagon and insulin that regulate the cytosolic form. Alternatively spliced transcript variants have been described. [provided by RefSeq] |
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| Location | | Chromosome: 14 Locus: 14q11.2 |
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| Gene position | | 24563483 - 24573339 Map Viewer |
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| Gene orientation | | plus |
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| Gene size | | 9857 bp |
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| Gene sequence |
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| OMIM ID | | 261650 |
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