Entrez gene ID | | 51060 |
Official gene symbol | | TXNDC12 |
Full name | | thioredoxin domain containing 12 (endoplasmic reticulum) |
Aliases | | ,AG1,AGR1,ERP18,ERP19,PDIA16,TLP19,hAG-1, |
Gene summary | | TXNDC12 belongs to the thioredoxin superfamily (see TXN; MIM 187700). Members of this superfamily possess a thioredoxin fold with a consensus active-site sequence (CxxC) and have roles in redox regulation, defense against oxidative stress, refolding of disulfide-containing proteins, and regulation of transcription factors (Liu et al., 2003 [PubMed 14557066]).[supplied by OMIM] |
Location | | Chromosome: 1 Locus: 1p32.3 |
Gene position | | 52521047 - 52485803 Map Viewer |
Gene orientation | | minus |
Gene size | | 35245 bp |
Gene sequence |
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OMIM ID | | 609448 |
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