Database of mammalian genes
Home

Home Search Browse Statistics User guide FAQs Links Questions Contribute Download


Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for MRPL4 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID51073
Official gene symbolMRPL4
Full namemitochondrial ribosomal protein L4
Aliases,CGI-28,L4mt,MGC16367,MGC2681,
Gene summaryMammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Sequence analysis identified alternatively spliced variants that encode different protein isoforms. [provided by RefSeq]
LocationChromosome: 19   Locus: 19p13.2
Gene position10362640 - 10370736  Map Viewer
Gene orientationplus
Gene size8097 bp
Gene sequence
OMIM ID611823