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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for VPS28 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID51160
Official gene symbolVPS28
Full namevacuolar protein sorting 28 homolog (S. cerevisiae)
Aliases,MGC60323,
Gene summaryThis gene encodes a protein involved in endosomal sorting of cell surface receptors via a multivesicular body/late endosome pathway. The encoded protein is one of the three subunits of the ESCRT-I complex (endosomal complexes required for transport) involved in the sorting of ubiquitinated proteins. The two other subunits of ESCRT-I are vesicular protein sorting 23, also known as tumor susceptibility gene 101 (TSG101), and vesicular protein sorting 37. Two alternative transcripts encoding different isoforms have been described. Additional alternative transcripts may exist but the proteins encoded by these transcripts have not been verified experimentally. [provided by RefSeq]
LocationChromosome: 8   Locus: 8q24.3
Gene position145653927 - 145649000  Map Viewer
Gene orientationminus
Gene size4928 bp
Gene sequence
OMIM ID611952