Entrez gene ID | | 51160 |
Official gene symbol | | VPS28 |
Full name | | vacuolar protein sorting 28 homolog (S. cerevisiae) |
Aliases | | ,MGC60323, |
Gene summary | | This gene encodes a protein involved in endosomal sorting of cell surface receptors via a multivesicular body/late endosome pathway. The encoded protein is one of the three subunits of the ESCRT-I complex (endosomal complexes required for transport) involved in the sorting of ubiquitinated proteins. The two other subunits of ESCRT-I are vesicular protein sorting 23, also known as tumor susceptibility gene 101 (TSG101), and vesicular protein sorting 37. Two alternative transcripts encoding different isoforms have been described. Additional alternative transcripts may exist but the proteins encoded by these transcripts have not been verified experimentally. [provided by RefSeq] |
Location | | Chromosome: 8 Locus: 8q24.3 |
Gene position | | 145653927 - 145649000 Map Viewer |
Gene orientation | | minus |
Gene size | | 4928 bp |
Gene sequence |
| |
OMIM ID | | 611952 |