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Gene information for AADAT (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID51166
Official gene symbolAADAT
Full nameaminoadipate aminotransferase
Aliases,KAT2,KATII,
Gene summaryThis gene encodes a protein that is highly similar to mouse and rat kynurenine aminotransferase II. The rat protein is a homodimer with two transaminase activities. One activity is the transamination of alpha-aminoadipic acid, a final step in the saccaropine pathway which is the major pathway for L-lysine catabolism. The other activity involves the transamination of kynurenine to produce kynurenine acid, the precursor of kynurenic acid which has neuroprotective properties. Two alternative transcripts encoding the same isoform have been identified, however, additional alternative transcripts and isoforms may exist. [provided by RefSeq]
LocationChromosome: 4   Locus: 4q33
Gene position171011372 - 170981373  Map Viewer
Gene orientationminus
Gene size30000 bp
Gene sequence
OMIM ID611754