| Entrez gene ID | | 51191 |
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| Official gene symbol | | HERC5 |
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| Full name | | hect domain and RLD 5 |
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| Aliases | | ,CEB1,CEBP1, |
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| Gene summary | | This gene is a member of the HERC family of ubiquitin ligases and encodes a protein with a HECT domain and five RCC1 repeats. Pro-inflammatory cytokines upregulate expression of this gene in endothelial cells. The protein localizes to the cytoplasm and perinuclear region and functions as an interferon-induced E3 protein ligase that mediates ISGylation of protein targets. The gene lies in a cluster of HERC family genes on chromosome 4. [provided by RefSeq] |
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| Location | | Chromosome: 4 Locus: 4q22.1 |
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| Gene position | | 89378268 - 89427314 Map Viewer |
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| Gene orientation | | plus |
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| Gene size | | 49047 bp |
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| Gene sequence |
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| OMIM ID | | 608242 |
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