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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for ABI3 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID51225
Official gene symbolABI3
Full nameABI family, member 3
Aliases,NESH,SSH3BP3,
Gene summaryThis gene encodes a member of an adaptor protein family. Members of this family encode proteins containing a homeobox homology domain, proline rich region and Src-homology 3 (SH3) domain, and are components of the Abi/WAVE complex which regulates Rac-dependent actin polymerization. The encoded protein inhibits ectopic metastasis of tumor cells as well as cell migration. This may be accomplished through interaction with p21-activated kinase. [provided by RefSeq]
LocationChromosome: 17   Locus: 17q21.3
Gene position47287589 - 47300587  Map Viewer
Gene orientationplus
Gene size12999 bp
Gene sequence
OMIM ID606363