Entrez gene ID | | 51225 |
Official gene symbol | | ABI3 |
Full name | | ABI family, member 3 |
Aliases | | ,NESH,SSH3BP3, |
Gene summary | | This gene encodes a member of an adaptor protein family. Members of this family encode proteins containing a homeobox homology domain, proline rich region and Src-homology 3 (SH3) domain, and are components of the Abi/WAVE complex which regulates Rac-dependent actin polymerization. The encoded protein inhibits ectopic metastasis of tumor cells as well as cell migration. This may be accomplished through interaction with p21-activated kinase. [provided by RefSeq] |
Location | | Chromosome: 17 Locus: 17q21.3 |
Gene position | | 47287589 - 47300587 Map Viewer |
Gene orientation | | plus |
Gene size | | 12999 bp |
Gene sequence |
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OMIM ID | | 606363 |
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