| Entrez gene ID | | 51257 |
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| Official gene symbol | | MARCH2 |
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| Full name | | membrane-associated ring finger (C3HC4) 2 |
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| Aliases | | ,HSPC240,MARCH-II,RNF172, |
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| Gene summary | | MARCH2 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH2 reduces surface accumulation of several glycoproteins and appears to regulate early endosome-to-trans-Golgi network (TGN) trafficking (Bartee et al., 2004 [PubMed 14722266]; Nakamura et al., 2005 [PubMed 15689499]).[supplied by OMIM] |
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| Location | | Chromosome: 19 Locus: 19p13.2 |
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| Gene position | | 8478187 - 8503901 Map Viewer |
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| Gene orientation | | plus |
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| Gene size | | 25715 bp |
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| Gene sequence |
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| OMIM ID | | 613332 |
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