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Gene information for PCSK2 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID5126
Official gene symbolPCSK2
Full nameproprotein convertase subtilisin/kexin type 2
Aliases,NEC2,PC2,SPC2,
Gene summaryThe protein encoded by this gene belongs to the subtilisin-like proprotein convertase family. The members of this family are proprotein convertases that process latent precursor proteins into their biologically active products. This encoded protein is a proinsulin-processing enzyme that plays a key role in regulating insulin biosynthesis. It is also known to cleave proopiomelanocortin, proenkephalin, prodynorphin and proluteinizing-hormone-releasing hormone. The use of alternate polyadenylation sites has been found for this gene. [provided by RefSeq]
LocationChromosome: 20   Locus: 20p11.2
Gene position17207631 - 17465223  Map Viewer
Gene orientationplus
Gene size257593 bp
Gene sequence
OMIM ID162151