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Gene information for MRPL35 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID51318
Official gene symbolMRPL35
Full namemitochondrial ribosomal protein L35
Aliases,L35mt,MRP-L35,
Gene summaryMammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Sequence analysis identified three transcript variants. Pseudogenes corresponding to this gene are found on chromosomes 6p, 10q, and Xp. [provided by RefSeq]
LocationChromosome: 2   Locus: 2p11.2
Gene position86426556 - 86440477  Map Viewer
Gene orientationplus
Gene size13922 bp
Gene sequence
OMIM ID611841