| Entrez gene ID | | 5133 |
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| Official gene symbol | | PDCD1 |
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| Full name | | programmed cell death 1 |
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| Aliases | | ,CD279,PD1,SLEB2,hPD-1,hPD-l, |
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| Gene summary | | This gene encodes a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases. [provided by RefSeq] |
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| Location | | Chromosome: 2 Locus: 2q37.3 |
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| Gene position | | 242801058 - 242792033 Map Viewer |
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| Gene orientation | | minus |
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| Gene size | | 9026 bp |
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| Gene sequence |
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| OMIM ID | | 600244 |
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