Entrez gene ID | | 51366 |
Official gene symbol | | UBR5 |
Full name | | ubiquitin protein ligase E3 component n-recognin 5 |
Aliases | | ,DD5,EDD,EDD1,FLJ11310,HYD,KIAA0896,MGC57263, |
Gene summary | | This gene encodes a progestin-induced protein, which belongs to the HECT (homology to E6-AP carboxyl terminus) family. The HECT family proteins function as E3 ubiquitin-protein ligases, targeting specific proteins for ubiquitin-mediated proteolysis. This gene is localized to chromosome 8q22 which is disrupted in a variety of cancers. This gene potentially has a role in regulation of cell proliferation or differentiation. [provided by RefSeq] |
Location | | Chromosome: 8 Locus: 8q22 |
Gene position | | 103424495 - 103265569 Map Viewer |
Gene orientation | | minus |
Gene size | | 158927 bp |
Gene sequence |
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OMIM ID | | 608413 |
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