Database of mammalian genes
Home

Home Search Browse Statistics User guide FAQs Links Questions Contribute Download


Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for UBR5 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID51366
Official gene symbolUBR5
Full nameubiquitin protein ligase E3 component n-recognin 5
Aliases,DD5,EDD,EDD1,FLJ11310,HYD,KIAA0896,MGC57263,
Gene summaryThis gene encodes a progestin-induced protein, which belongs to the HECT (homology to E6-AP carboxyl terminus) family. The HECT family proteins function as E3 ubiquitin-protein ligases, targeting specific proteins for ubiquitin-mediated proteolysis. This gene is localized to chromosome 8q22 which is disrupted in a variety of cancers. This gene potentially has a role in regulation of cell proliferation or differentiation. [provided by RefSeq]
LocationChromosome: 8   Locus: 8q22
Gene position103424495 - 103265569  Map Viewer
Gene orientationminus
Gene size158927 bp
Gene sequence
OMIM ID608413