Database of mammalian genes
Home

Home Search Browse Statistics User guide FAQs Links Questions Contribute Download


Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for PDE3A (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID5139
Official gene symbolPDE3A
Full namephosphodiesterase 3A, cGMP-inhibited
Aliases,CGI-PDE,
Gene summaryCyclic nucleotide phosphodiesterases (PDEs) comprise a complex group of enzymes, and at least 5 major PDE families or classes with distinctive properties have been identified. Members of the cGMP-inhibited cAMP PDE (cGI-PDE) family, such as PDE3A, are characterized by high affinity for cAMP and cGMP and competitive inhibition of their cAMP hydrolytic activity by cGMP and certain positive inotropic agents (Meacci et al., 1992 [PubMed 1315035]).[supplied by OMIM]
LocationChromosome: 12   Locus: 12p12
Gene position20522197 - 20833881  Map Viewer
Gene orientationplus
Gene size311685 bp
Gene sequence
OMIM ID123805