Entrez gene ID | | 5139 |
Official gene symbol | | PDE3A |
Full name | | phosphodiesterase 3A, cGMP-inhibited |
Aliases | | ,CGI-PDE, |
Gene summary | | Cyclic nucleotide phosphodiesterases (PDEs) comprise a complex group of enzymes, and at least 5 major PDE families or classes with distinctive properties have been identified. Members of the cGMP-inhibited cAMP PDE (cGI-PDE) family, such as PDE3A, are characterized by high affinity for cAMP and cGMP and competitive inhibition of their cAMP hydrolytic activity by cGMP and certain positive inotropic agents (Meacci et al., 1992 [PubMed 1315035]).[supplied by OMIM] |
Location | | Chromosome: 12 Locus: 12p12 |
Gene position | | 20522197 - 20833881 Map Viewer |
Gene orientation | | plus |
Gene size | | 311685 bp |
Gene sequence |
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OMIM ID | | 123805 |
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