Entrez gene ID | | 51434 |
Official gene symbol | | ANAPC7 |
Full name | | anaphase promoting complex subunit 7 |
Aliases | | ,APC7, |
Gene summary | | This gene encodes a tetratricopeptide repeat containing component of the anaphase promoting complex/cyclosome (APC/C), a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell cycle regulators such as B-type cyclins for 26S proteasome-mediated degradation through ubiquitination. The encoded protein is required for proper protein ubiquitination function of APC/C and for the interaction of APC/C with certain transcription coactivators. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq] |
Location | | Chromosome: 12 Locus: 12q24.11 |
Gene position | | 110841535 - 110810705 Map Viewer |
Gene orientation | | minus |
Gene size | | 30831 bp |
Gene sequence |
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OMIM ID | | 606949 |