Entrez gene ID | | 51455 |
Official gene symbol | | REV1 |
Full name | | REV1 homolog (S. cerevisiae) |
Aliases | | ,FLJ21523,MGC163283,MGC26225,REV1L, |
Gene summary | | This gene encodes a protein with similarity to the S. cerevisiae mutagenesis protein Rev1. The Rev1 proteins contain a BRCT domain, which is important in protein-protein interactions. A suggested role for the human Rev1-like protein is as a scaffold that recruits DNA polymerases involved in translesion synthesis (TLS) of damaged DNA. Two alternatively spliced transcript variants that encode different proteins have been found. [provided by RefSeq] |
Location | | Chromosome: 2 Locus: 2q11.1-q11.2 |
Gene position | | 100106480 - 100016938 Map Viewer |
Gene orientation | | minus |
Gene size | | 89543 bp |
Gene sequence |
| |
OMIM ID | | 606134 |