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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for PDE1B (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 5153 Official gene symbol PDE1B Full name phosphodiesterase 1B, calmodulin-dependent Aliases ,PDE1B1,PDES1B, Gene summary Cyclic nucleotide phosphodiesterases (PDEs) catalyze hydrolysis of the cyclic nucleotides cAMP and cGMP to the corresponding nucleoside 5-prime-monophosphates. Mammalian PDEs have been classified into several families based on their biochemical properties. Members of the PDE1 family, such as PDE1B, are calmodulin (see MIM 114180)-dependent PDEs (CaM-PDEs) that are stimulated by a calcium-calmodulin complex (Repaske et al., 1992 [PubMed 1326532]).[supplied by OMIM] Location Chromosome: 12   Locus: 12q13 Gene position 54943177 - 54973023  Map Viewer Gene orientation plus Gene size 29847 bp Gene sequence >PDE1B:17086483..17116329:Length=29847 ACTCGTCCCCGGCGCCTGTGTGCGTGCGCTCGCCCTTGGGCGCTTCTGTCTGTGTGTGCC CCCGGCTTCCAATCGTTCCTTTGGGAGGGGGAGGAGTGGCTGTGAGGAGTGAGAGACTGG CGGGCAGGCTGAGGAGAAGGGAGGGAGAGCAGAGGGAGGGGGGAACCCGGCCGGGGGAGG AGGAGAGAGGCGAGGAGGCGGCTCTGGCAGCGCGCGGCGGCGGCGGCGGTAGCGGCAGCA GCAGCGGCGGTGCGGAGAGCTTGGACTGGGAGCCCAAAGCTCGGCTGGGCAGCGGGAGAG GAGGAGCCGCAGGAGCTGCAGCTCTGCCAGCTTGGGCCGAGCCTAGAGACACCGGCCTGG CTGGTCCACGCCAGCCGCAGGTGGGAAGGGCCTGGGATGGGGGGTGAGGGTCTCTCGGCT GGGGCTGAAGCTGAGCCGAGGTGCTGTCTCCTCCTTCTGTTCCGTAGACCGTGGCTGAGC ATGGAGCTGTCCCCCCGCAGTCCTCCGGAGATGCTGGAGGAGTCGGATTGCCCGTCACCC CTGGAGCTGAAGTCAGCCCCCAGCAAGAAGATGTGGATTAAGCTTCGGTCTCTGTAAGTC CCCGGCCCGGGAATGGGGGGAAGGGACCTTAGGGAGCCTGAGCGGGAGGAGGAGGGGGGA TAACTGGAGCAGGGCTGTGGGCTGGTAGATTCTCTTTGGCACAGATGTTGGCAGGTGCGA GGAAGCACGGCCCTGACACGCGTGGCCAGGCCACATGTGCAAGGCATGTGCGGAGCAAGC TGGCCAGTTGGAGCGGGCTTAGGAGTTGCAAAGGTAACGATGTGCCTGTGCCTGTGGACC CCAGGCTGACACACGCAGCGCCTAGAGGCAGCACAGTATATGCAGTGTGGCAGGGCTGCA GGAGGGCAGTAGAGGTGCCAGGCTGACTCACACATATCCATGTGCAGAGTTGTGCAGATG TGAGCCACATGACATGTGTGTGCATGAGTGAGCGTGGGTCACAGAGGTATGTGGAGTGAT TGCACACAGCTGTAGATCTACTGCATGGGAATACTTGTGCCAACCTGTGGGTCATATGTA TCTCAGTTGGGATTGGTAGTTTCTGCCTCATGCACAGGAAGTGGGGTGGGGGTTACCCCA TGCCTGAGCTGCTCATCTCTTGGGGCCTGGAAACTCACTCTATGTATTAATGATGAGGGG ACCCACGTGGAATCTGGAGGGGGGGTTGGAGCCCCCACCTGGAAGCTGAAGGAGGTGATG ATGGTGAAGAAATATTGATTGACAAAGGCAAGGTAACTGGCTTAATCAGAGGCTTTTTGT TTATATAGGGTCTTCCAGGATCTCCAAGCACATTTGGGCATCTTTTCCTATTGTTGCAGT ACCAGGGCATGTGGGGAGGAATAAATGGGGGAAGGAAGAACTCAGGTATCTGATACTCCA GTCCCAGGGGAGGAAAGGAACTTTTCCCCTGCTCCTTAGAAAAAAAAGAGGATTGGGTCA AAGACAAGCCATGCACCATGTTTATCTCCCAGTCAGCTGCTGCCATTGGGAAATCTCCGC AGTCTGTTGATTCTTAATCAGGGAACAAGAGAAGATGTCCCTCTCTCCGAGATGAATCCA TGGCCCCAGGAAAGAGGAAACAGATAGGAGACTATGGATGTTTAGAGAGGAAACACAGTA AACATAGCCCTGAACCCAGTTCCTCCTCAATGTTCTCCATAGTGAGCACCGAAGCTTTCT ATTTCTGGGTTCTGGGAGAGGGAGAGATGGGGGTAGGGGATGGATAGATGCTTATGTTGT ATTGTTCTTTAAATACTTCACCTATGGTGATAAGATGACACCTTTTTATGGCAGATGGGT CTGATTTATACACTAGCTACTTGGAGAGGCGTTAGGGAGAACTGAGGCATAGTGGGCAAC AAGGCTTGGAATCCAAATGTACTTCTCAGTCCTCCTCCTTGGCTGCCTCTGGCCAATCCA ATTTGCTGGGCTCTATGAAGCACAGCCTTGGAATGAGTTCTGGGATGAAGAAATGGAAAA CCAGATTGAACTGATTTTTGTTGGGAGGAGCACTGTGTGATTCTTGATAGAAAATGACGC TGCGTTAATGGTAAATGAGCTGGGGAAAGGGGCAGATAAGGAAGTAGTTGAAAGGTAAAG AAGGGCCCCAGGTCCATAAATGGGAGAATTCAGGATGGCTCCCCTAACACTAGTGGCTCA TCATACTTACCTTGCCTGTATTCCAGGTAACAGGGCCCTGCGAAAGAGTGGGTATTACTA GTTTCACTATCTCCCACACATTTCTAACCAAAAGCCTTTCCTGAAAATGAATTGTTGTTT CTTCCTTTAGTGTGAGAAGTGCTCAGTGGTGAGAGAAGAGGATTCCCAGAAGGAGGCATG AAACCTGGGAAGAGAAGGGAGTAGAGGCATCTGTCTCTCCAGAGTGCCTTAGCTGAGATG TCCTTACATGAGATTAGGGTGGACAAGGATCCCTATTCTTATTGATTAGATCATTCTGGT CTTCACTCACTTCAGCAGTCTGGTCCTTAAGAATGCTAGCTTTGTACAATAAATTTACAA GTAAAAAATAAAGCTAGCTACATGTAATATAACTTACCCAAAAAAGTACAATCTCCGGAT TATTAATTGGCAGGAATAGATTCCCAGTCTTACGTCCTTAAAGCAGAGAAAGACCTTGAA ATCAAGGTAGATCCCAACTTGATCTATGTTGATGGCCTACTGGATTTTGCCTTTTTGAAT ATTGGGGAGGCTTTGACTATCAGATGAAGGGAAATAAAAGGATTTAGGGCTTTGCTGGGT AAGAGGTGGGAGTTTCCCAACCCTCTCAATGGGATGGTTTCTGAATAGGTGAGAAAGGAG ATGTTCCCCCTTTTAAGTGGAAATAAAGATCCCCCTGCCCCTTTGGTCAAGGTGGGAAGG GGTTGCTAAGTCTGGAAATAGGAAATAGACATGATTATCTTAGGACTGGGTACTGCTTGG AAATGGAAACATGGCATATATACTTGTATGTATTTATCTAACTATCTATCTAGATTCTTC TACTCAACACATCCTATTCCCCCCCTTCTACCCTTTTAATTTCTAATCAGGACATCCAGA CTTTCTTCAGGGAGACTAGGCCTGGTGTTTTTGACTCTGGATAAAAAGCCCACACTAATA TAATAGTGCAGGGCAATTTTTTGTTGGGAAGAGCATCCAAGAATTCTGTTTCCCACACTA AGACCCTGTCAAAAATAAATTCAGAATCTAATCTGTATCATATGAGCTGAAGAGAATCTC TTAACTGTGTGATTTTACCCCTATTTTCAGAACAATTTCTCTAATTAAGCAAACTCATAA ACTGAGGCATGAGAGAGGGTGAAAGAGGCCATCTGGAGATGATGAGTTGGCCAGGATGAT TTTCAGCATCTGTAACCCTAAGAGGAAGTATTTGACTTGGCTGTCCACCCTTCTCTGAGA TCAGAGGGCTTTAGGGAATGGGAAGAAGACCAGAAGAGATAGAAATGATTTTCTGTGTCT TTTGTGATTCAAGAAAAACGATGAGCAGACATTGGTTTGCCATCCTCAGCTCATTTATTT ATCCAACAACTATTTCTTGAGTGCCTTCTATGGACCAGGTGGCATGCTGGATGCTGAGAA TACAGTCGGTGGTGGACAAAACAGACATAGTCCCTCTTCCTACAGAGCTTGTAACCTGCT TCAACTCCATCAAGTGGTGTAGAGAGGCAGGGGGCTCTGTATTCCCTGTTTTGCTACACC CACCCAAGTGATGAAATTCTACCACTCTGGGTTTCTGCCTCATTTTTTCTTTAGGGGGGT TATATACATAGGAAAAGCATAAATATGAGTTCTCTTTTTCCCAGGATGGTACAAACACCA CTCTCTTTTCTCTGCTCCAGTTTCTCTTGGAATTTTACATTTTACAGATGGAACTTCCCC CTTCCTTTGGGACAGTATAGACATAGTCCCTTTCTCTTTTTCTTTCCCCACATGGTACGC ACTCGGGACCCTCAAAGTCTAGGCTCAATGTTCTATGCTGTGGTTCAAGGTCATTATAGA TGAGCTGGAGCAGGGACCCCACTGGGGATTATTTTTGCTTATCTTTGTTTCATCAGAGTC TAGTGTGATACCTTGAACATAACAGGCACTCAATAAATGCTGTTAAATAAAGGAATGAAC AAATGAAATAGTGAATATATGTACATATGTTACGAGGTCCAGTTCTGTCTCTGGTTCTGT GGTGCGTGTATACCTCCGTGTTTGTTGAGTGGCGGGGGGAGGAGTAGGAAATGGAGGTGG AGGAAAGGGAGATGATGATGATGCTGTTTTTTTGAGAGGGTGATGCTTAAAAGATATGGG GTTTAGGGACCTCAGGACAGAGCCTGGAACTGAAGGAGTTACAGAGAGGATCCAGAAACT GTGGCGTTTGGATTGTGTGAATGAGATATGTTAGGATGAAATTGTGAATGCCTGCCTGAC ACGTATACATGTGTTTGGGTAAAGGTTGATATGTATGCTGGGGACAGAGCTCCATGAAGA TGTGTCTGTTTTTATAAGTGGCATGTGTAATAATAAATATATTGGGAAGGTGTGCACTTA CCTGAATACCTGAAATTGTCCTAGTTATGAGATGATGTATGTGTGTATGTAGGTAATGGG ATAATACCTATGTGTGATCTTGTGTATGTATTTGTGACACTGAGATTTTTTGACATTCCT GGGGAGATCCAGTGGATGGGAGGAAGAAGCTGAGACTGGGTGCCTCATTGGTTTAACCCT GGCTTTTGCCCTCTTTTTGTATAGGCCCCATGGAGTGATCTTCTATGGTTCTTACCAGTT TTGAAAATCATGCTGCCATTCTCCTTTTTCTGTCTATGGATGTGGAGCTGCTGTGAAGAT TGCAGCATAAACTATGGTTCCCTGGACCTCTGGAGAAAAAGGAGTGTCATTTTTCTCATG CCTTGGTGGGGACAGTTTTTTAGTGCTATCCTCAGCAGATTAGTCCTTCTTCCTCTGCTT CCAGCCATAGCAAAGGGAATCTCTTCTCCCTCGGTTTCATACCCCACTTTTCCATCAAAT GTCTCCTGTCTCTATTTCCTCCATCAGCTTTGTCTTGAATGAGGACTGTGTGGTATCTCT GGGAAGGTAGAGGGTAGAAAATTCCTGCCTTAAGTTGAAGGGAAGGTGCAGAGGTAGGGG ATCAAATTCAGCCCCAAGGAAGAACTTCACAAACCTCTGGTCAGGATAGGTGGCTGGAGG GAGGGAAGCAGGGAGGCAGAGTGGTGGTAGTGGAAGGGCATGGGGAATTTTGGGAGACTT GAGTTCGAGTTCACATTCTGCCCTAACAATTACAACGGTGTAATCTTTAAGTCACATAGT CTCTCTGAGTCTCAGTTCTTCATTTAATATCATCATGTAAAAGTAACTTTGAAATGATAA AGCCTGAAGGTCTTTTTCATCATGGGAGAGCTTGCTTTGTGAAGAGGCAGGGGAATGGGA ATGGATGGGCAACTATTGGCTGGGATGAGGGAGACAAAGATTCAAGAGGTAGGAATATGA ATTACCTAATAGGTTTGAGCCGTGATTGAAGGAGTCTTGTTGATGGTTATCTGGAAGGAG TGAAGGCATGTGTCTGAACTTAGAGACCAGAAGGATAGGTGGGACTAGAGGAGGGCAATA TTATGAAGGATGTGGGCCACTGAGGTCAAAAGAAAGGAGAGGAACTTCCTCCTTATCATT TTTTCCCAATGGTCAAACTGGAAGTGGATGGAGCAATTGCAGTTCTGAGACATGGTGAGT GTGGGAAGCCCAGGGGCTGCCATAGGTGGGTTCTATGAACATTGGGGAATTCCCTTCGGA CATTTATCCCAAGTCCCTAGGCCTGAGGGTATCATCAGTTATACCACATCCTATTTTAGA AAATCACTGAAGTCTCTTAGAATCCAAATATCACTCTGCTTGTCCAGGAGCCTCAGGAGG TGGTTTGAAAAAAGACAGAGGATTCCACATTTGAGGTTGCATTTGCCACCTTTGCCCAGA GGAAGGCGAAAGAGGTTGGGGATGCATGGGACTAGAAGGCCAGGTGAGATGCTCAGTAGG AAAGAAGCCTGCACATCTATATAACTACACCCTGCCAGGGAGTTCCTGAAATCAAAGGAA TGGTAGCTTCCCTATCTCCCAGATTCCCCCAACCTTTAAATCTTTCTGCCACCTTCAGAC TGGGATGGAGGAGCAGAAAACCTTGAAAACAGGTCTTCCCTCTCTTTTTGAGTCTTTAAA GGAATCCTTGAGAATTTGTGTCCAACTCCTCTGCTCTCTCTCATTTTCTCTTCTTTGATT CTTCCATCTTCTCCTTTGCCTCATCTTTCTCTGGGTTCTCTTTCGCTATGAGGCTCCCTT TTGCTCTTCTCCCTTGTCCCACTTCCTCTCTCTGTCCCATTCCTTTTGACTTACCCTTTC GCTCTTGCCATCAGTACTTCTCCTCCCTCATCTTGGCTAGGAGTCAGAAAATCCCCGTGG CTCCCTCCCCTCACTGAGGGGTTGCTGTGGTGATGGTACAGGATAAGCTTGCTATAGGTG CCCTCTGGGGCCTTAGGAGTCCAGCCCCGACTCCTGTCTTCTGCAAGGCGTGTCTTTTGC CTTCTCAGTGACCTCATCCTCCTAGTCCCTCTGGGGAGGAAGCCAAGTAATTGCCTTTGA ATCTCAAGGGGCTGATTTTTCTCAGGTACGGAAGTTGAGTAGCTATTTTCCAACTCTCTT CAGGATAGCAGCAGAGAAAGAGGGACAAAACCAGGACAGCAGGTGGGGTGGAAGTGAGAC AACTGGGGAGACTGGAAGTTGTTAGATAATGAAATTGTCCCCTAAGGCAGCAAGACTACA TGGTCTGAGAGAACTGTGGGACCATTCCTCCGTTCCTTTGGGAAGGGGCATAGATGGGAA TTGAGCAGGGAAAAAAGAGTGACTGAGAAGGGAAAAGGATAAAATCAACTTATTATCCAT ACAATGCAGGGAGGTCCTTAGTGCCCCTGCCCTTGCCCCTGTGCCCTAGTATCCCCCAGT CCTGCAACTGCTCCTTTTCCCTCAGCTGGGGTTGCATCTATGGAGCTTATCGCTGTCTGA GAAGAAAACACCAGGTCCAGATTCCACTTCAGCACTCAGACCTGGCAAAGGTGCACTGAG GGAGATGTGTTGGGGTTTTGGTAGAGAGGAAGGCTTGGTGGGAAAAGGGTCAGGTTGTTT TTGGGGTAAGGCCTGGGGGCATAGGGCATGGAGAAGAGCTAGAAAGGGGGTGCTTCAGGT GGTGCTGTTGGAAAGAGCCAGACTTCCAGGTCAGTTGATTCCACAGCTGCAGTGAGAAGT CAGATTTGCAAATAATTATGGTGGCTACAGTGGGGTGATTAGGCTGCCAGCTGGTGTTGG CACCATTTAGGTTGGGAAGGGAACTTGGCTGGTGGGGGGTTGAGGGCTGGGGGCTGGGGG CTGGGGGCTGGTTGTAGGGAGAGGCTGAGTGATTCTCTGGCAGGCAGGACCTGGGGAAAG TTTTTCCTTTTATTCCTATTTGTTGGCTTCCCTGCTCCCCTGTTTATCAACTCCTGCATA TCTGCTTGGCACCATGTCCCTAGTTCTCTTCTCTGTGCCCACCTTGTTTGGAAACTTCTT GTGGCCTGGACTGAGTGAACACACAGGCCAACGGAATTGCCAAACTTCCTAAACCATGAG CATCTCTCTTCCAAGCAATTGCTTTAGAAATTCCAATCTGGAAGATGTATAATAAATCAA ATTGCACTAGACACCTCAAAGACTTCTTGGTCCCTCCTATTCTCTCCCCTTCTGCTCTTC TTTGAAATGCCAAGAAAATTTGCTGTTGTTTTTTAAATTGCAGTGAAATAAATTGAAGAC AGATATGCAGGAGAACTTCCTGGAAAGTTCCTGGAGGTTAGACTGTGGCCTTTCTCTGAT AAAGAAAAAATCTACCCTTCTCCTCTAAGCACTGGGTTAGAGCTGATTTGGGGAAGCAGT GAGCCAGTCAGAAAGGATGAACTCTGGAACTGGGAAATTGAGGCCCAAGCATCCTACTTC CCCAGTGTCTCCAACCCAGTCCCTGAATCTGAGAACCATAAAGGCTACAGAGGAGGAACA GATCCCCAGAGATAGTTAGTAAAATCGGGGCAGTGCTGGGACCAGACCCAAATCCTGCTG ATCCATAATCTGATGCTGCCCTCATCACACTTGCAGTCAGACTCTTGCTAAGCTTTTAAT TTACTTTCCCATCCCAGACTACCTTCAACATCTGTTAGGCCCCATGGAAGCAGGGCATCT GCTGGGAACAGCTGTTAGGATGTAGTTTGGAGGGCTGGTGGGGTGGTCCATGTGGAGGTG GTTAATGAGCAAAATCAAATGGTGTAGGGAGGGAGAAGAGGGGTGGAGAAATGAACCAGA GAAAGAGTTCTTCTGGACTGGGTACTGGGAGCCTCCTCTTTAGTTTGCCTTCCTCTGACC TTCTCACCCACCCCTCCCAATTCCTCTCTCTCTCAAGGGCTGAAGTCTGATGGAAAGGTG ACTCATTTGTGTTCTTGGCTGGGAGCTGGGACACCTGGGTTCTTATTGGTCTGGGCTGAG GCTCAAGCTGCTTAGATTATTCCCTTTCTCGTGTGATCTGAGTTGTGCTGGGCTGTTGCT AGGAACACCTGTTAGAAACGGCTTCTGGTCAGAAGGCACAGGCACAGGAGGAGTCTGAAA GCAGTCTCTCCCACTTCTTCAGTGTGTTCCCAGCTTCTCGAATGCAGCACCTTTCAAATC TCCTTTCCTTTCCTCCCTGCCCCCTTAATACCTCCTACCCCTTTTCCTCATCTCCCTTCA CCCTCCTGGTTTCTGTCCTTCCCCCACTATCTTCCAATCTTCCCTAGGGCCTGCCCCATT CCCTTTCCTCATCCCACCCCCACCCGTAGCTCCTCTGTCCAGTGCTGAGGGCTCTCTCAC CACTGCTGCCATGTCAACAGTGCCTCCCAGGATGGCAACCCAGCTTTGCCACTGGGGGGC TATTTTTATCTGTGGAGCCACCCCCGCCACAATGCCCAGCCAGCTGCCAGAACTGGGGCT TTCTGTATAGCAATGGAAGCCAGAAGCCAGGGGAGTGGGGGAGTGGGAATGCTCGGGTGA GGTGGAGAGCTGGTTGTTCTTGGTTTCTGGAGCTACATGCTCTACATACTCTGCAGCCTC TGCCTCCACTGCCTCCCCAGGGCCTCTGGAATAAGAAGCCAGAGAGAAGCCCTAAACGTC CAGAGTGGTGGCGTCAGGGAGACTAGAGCTTTCCCACCAATATCCAGGTGCCATCTGAGG CCTGGATGGAAAGTCAGGGGTCCTGGCTGTAAGAGTGGGCATATGGGACTTTGTTTATGA ATGACTCAATGAATATTTGCTGAACTAACTAAAGATTTGGACTAAATAATTATCCTTCAT ATTCATGTATCACTTTAGGGTTCCCAAGGTGTTCTCATACCATATCTCATTAGGTCCTTG TGAAAATTCTGTGAAGCATGTATTATTTACCCATTTTACAGACCAGGAAACTGAAGCTCA GAGTGACTTTCCCAAGGTCACACATAGTAATAAAATCTAGGCAAAAGTTTGTGATTTCTT TTTAAATTTAGTTTTTTCTTTTCAACTGAGCTAGCCAGAAAAGTCTCCTGATTTTATAAA CTTACGCCCTCTTTCTATTGGAATTAGATGATTTCCTTGGTTCTTTCAATTTCTGAGATT TTGGAGATTTGAAGTCAGCCAGTGAATCCCTTCCCGAGCACCCACCCCTTTACCCCCACC CACCCCCACCCCTTTACCCCCACCCACCCCCACCCCTTTTCTCTTACCAGAGGCAGAGTC TCCCATCCTTTGTTTCCTACCTCGACCTTATTCTTCACTGCAGGCTGGGCAGGCATTAGA GTTGGGTTCCTTTCTATTTTTAAACTACATTTAAGGGCTAAAGGAAAATCCATACTGGAC CCTTTGTTGAGGTCATCACATTTATGTCCTGCCTGCCAGCCAGGTGACAGTCTCCTTAGA GGTAGAGTGTGGGGTGTGTGTATATGTGTGTGTAAGTGTCTATGTGTGAAATTTTTCCTC AGGAAGGGATGATGGTTGATCATTATCCCTCCTTATTAGGAAGAGTAAATAATAATAACA GGCTAGGGCAAAGTATGCAGCATGCATACCTGGGCTGAAGTGGTGAGCAGCCATTCGTCC AACCAGCTTTGGTTCTAATGGGTAAGAGAGGAGAGGAATGGACAAGATATCCTCTTCGAG GCTTTTCTAGTCTAAGAAATCTTTACTTTTCATTAGGAGAGTTGAGGTTAGCACTTACTT GGCTAGAGTGGCAGGGTCTGGAGTGAGGGTACAAGACGAGGCAGGGAAGTTGGCCTGGGT TGGAGGTTATTAGTGTTTCAGGCTGTGTGCTGCCATCTGCCCCCACTCTCAGCCCCATCC TGCAACGCAAGCATGTCCACAGAACATGCCAAATGACCTGTCCTCATCTCCTGGGTGGCA TTCAGGGTCTCTGACACTGGGTCTAGTCCTTTCTCTCTAAAAACACTCATCAGCTTGTGG TCATTGTGGGGAGGGTGGTGGTGGGACACAGAAAGAGATGGATACAGAGAGAGTGGGTTT CTTCCCTCCCAAGATCTGCAGCAGCCCTGCTTCACGGCTACCAGGTGTTCACTAGAGAAC AGCCTTAAGATATTTGACTTCCACTCCTCTTGTTGAGATCGAAGCCCACTTCCACTTGTC CCAGTACTCAGTGGAACTGAGAAACAGCAGGTTCCCAAACTTCATTTATTTCTGATTCTT CAAGGCTTTGGCATAATGACAAGGTATTTTCATTTCTTCCTGCTTTTGACGGGTTGGGGT AAAGGGAAAACTTCCTGTTATAAAATCCTAGCTCTTGGCCTGTGTCTTCTCTTTTCCCTT TCTGCTGACATACTCAACCCCATTAGTTCCTTTTCCTCTTTACCACATCACCCGCAGCCA TAGACCTACATCTAAGAGATTGCAGATCCCTGAACTCTTTTCCCCAATGCGTTGGGCTTC ACCCGCCAGCTCTTCTCCTTAGCCCCGCCCAACTCCTCAGCTGGCCAATCACGGCCCCAG CGTACATGTATTGGTGGCGACATCTCCCAGCCAATCAGGAGGCGGGCTGGGACTGTGTGC GCACGTCCACTTGGAGCTGCAGAGGCTGGGTTCTTCCCTCCCCAACCTTGGCGAAAGCAA AGTCTGAAGGCGGGAGAGGGGTTCCTGGTCCTCAGACCCCTTCTGGGTGCCTCTTTTGGC CCCTCCTGGGCCATCTCATCGCTTCTCCTTACCTCTGAGCCGATTGACCTCTCTCTGGTT AATTCATGGTTATTCCCCAATTTCCATTTTACAAATGAGAAAACTGGGGCTGGGGGTGTT AATTTGCCCAATCCCTTGGTTTCTATGAGCGAGTTCTCTTGACTTTCCTTCTCTGCTTGC GGGTGGAGGGCCCTTCCCTCCCTGTTGAGCCCGGTCTCTGGATAAGGATCCCCTGACACC TAGCTTCAGGAAGCCCCTCCCTACAGTTTTTTATCCTCTGTGGGAAGTTCATCCCCCTGT CTTGCTTCCATTCTGTGAGGTGGGTTAAAGCTCGTTTTGAAGAATGGCCCCAGAAAAAGA CCCTGAAAGGGAGCTGAATCTGCTTAGCTCCTTTTGGGGGTTCTTGCAGGGCCCCTTCCC CTCCCGCTACAGACCTCCTCTCTGTGACAGATTCAGGATGGTTCCCTGTCCCTGCACTCT TAAGCCTCTTGCTAACCCCCTTTTTCCCAAAAGAGGAGCCCCACCTCCTCAGAGCAAGGG GCTGGCCTGTGCTATTTCTGTCCTTTCTGGGCTTCTTCTGAGAACAGATTCTTGTTTTCC GTCTGATTCAGATGTGAAACTTTTCCCGCAGCCTCCCCTCTCACCCAGTTCCGGTAGGCT GGGTCTCTGCCTCCCCACTCTCTTCTTCCTGCAGCCAGGCCCCTCCCCAAAGTTCTCTCT GGTCAGTTGCTCAGTTCTACTGGGACCTGGAGGAGGAAGGCAGGGGCCAAAGAGGAAGTT GTCCCCTCTTGGGGGCCCTGGGGCTCCTGGGGTCAGGATTTTGATACTCTGAAGCAGGAA ACTTTGATTCCCATGGCAAACCCTGTTCCTGTTCAGAGGAGCCACCTCCAGGGCCCCATT CTCAGGTAGGTGCCAGGGATGAGAAGAGGAAGGGGGAGGAGGGAAAGGACAGGTTGCTCA TGGATCCACCAGTTGTAGTTTAGTGAAGTGGAGAGATCAAGACCTGGCAGTCCCCCATAT GTTTTGTGCGTGTGTGTGTGTGTGTGTGTGCGCGTGCCAACTTCACCTTTTACTCTGTCC ATCTTGCCCTTTACCTTATTCTCCTCCCATTTCCATCCCCCCCCACCTTTGTAAAAATTG CTTCTTCTTGACTATGGTAGGTGACTTATCATTGTTTCTTCCTTTTCTCTCCTTCCTGAC TGCCAACATCCTTAGGACCTCACATTCCTTCGAAATTTCATCTTGTCTTAAGAACCCAAA CTGGAAATAGAATTCTTCTCTTGACTCCCATCCCCTATCTTATTCTAAAGTCCTTCAGAG TTAGAATCTCCCCAGACGCACTCAAAATCTTCACATCACTGTTCTTCTGCAGGAAGTCCT TCTCTGGCTTCCCTGTCCTAAGCCCCCTACTTATGGTGATCTTTTTGGGAATGTGGGTGC TGGAAGCGGAGGCAGGGGACTTTGGAAATCCCCAGAACACCAGCCATGGTGAGCCAAAGA AATGAACTGTAGAAGCTGGAGAAGCTGAGCTCTTCTGAGGTGTTGGGGTTATAACTGCCA GAGTCTTTTCCTCCCAATGGCTGCCTAGAGCTAGGAGAGACTGTGGACTTCCAGAAGTTG GGATCTGAGGCTTTTCCAATCGTGCAGGGACTGAAGGTAAAGCAGAAAGAAGTGGTGGTG GTGAAACGGGCAGGGATGGAGTTCGAAGGAAAGTTGGGGGAAGCTGCCAGTTTTCCTTGG GGCCAGATGTGGACTGGACGGGGTTGAGCATCCTGTTCTACAGGGAAAGGTACCTTTACT GTGCCAGATTCCTTGATGGCTGAAACAGAGGGTTTGGATTAAAACTGATGTTGGTGGGAT AGAAGGACTTCCTGCAGAAGAACAGTGAGGTGAGGACTTTGAGTGGTCTGGGGAGATCCT AACTCTAAAGGACTTTAGAATAAGAGAGGGCCCTGGCAGGCCAGAAAGTATGGGGTGTGT GTGTGGAGTGGGTTATTTGACTTCAGGAGGTTGCAGTTCAGCACCTTCAAGAGGGTGCTT TCAGCTGCTTGAGTCCAGGTCCTCTTCTTAGACTTCCCATTTGTCAAATTTATTCTTTAA TCTTTTTTCCCCTCCCTCCCTGCCTCCTTCTGGTGTCTGGATTGTGTTTGGTTCAGATTT CAACAGAAGCTATACAAGAGCTCCTGGACAAGATCTGTAAGTGACAGAAGGAGAAACTCG GAGGGAAACCTGTGCTTGAAGTCAACCTACAACCTTACTCTTCTCAGGCTCACTGTTATT TTTAGAAACCCTGGCTCAGAAATCTCCATTGTGAGCTCTGGGAGATAGCCTCACACCTGA TTAATTTTCCCCTTTCCGTTTTATTTATTTAATGAACTTTTACTGAGCATGTTCTGTGTG CTCTGAGGATGGAGGCCAAGATAAACAAGCCACTGTCAGCGTCATCAAGACACTCACAGT CTCCTATGGGCCAACCGACAGAATTAATTAAGGTTGGACCGGCTGAGACTGCAGAAGCTA TGGTGGAATGGGTTCCAGCCTCTCTCTAAGCTAACTGCATGATTAGGTTTGTTCTGCCTT AACAGCTTCATTGTTTGGGGACACGGTTAGGTTCCATTAGCTTGAGTTGTAGGCCTTGAC AACCTGACTGAGATGGATGAGTTGTGTGACCTTAGACAAGTCACTTAACCTCCCTGATAA GGAGTTTGTGAAGATTAAATGAAGTTTGTAATTGTAAAGGAAAGATCATGGCTATTATCT TTCTCCCATTTCCTCTGTTAGGGAGCTTCCTAATTACCAGCCTCAATCCAAACCAACTCA GTCTTCTCCATCTGGACTTGGGAGAGAGAAGGTACTTGTATTTGAAGGGAGTGTGGTGTG AGCTGGGTTAGGACCACCATGATTTGATGTTGATCAGTCAATTCCTATTCAAATTACATT TTTGGAGACCTTTTGTATGTGCCAGGCCTTTTAATGTATTATATCACTTAATCCTCTTAT TAATAGCCCTGTGAAATGTTTATTATCATCCTTACCACTTTATAGATGAACAAGTTGAGG CTCTAAGATAAACATTCTCAAAGTTTAGTGTATATTAGAATAATCTGGGGTGTTTTTTAA AAATGCAGATTGGGTTGCGAACTGTGGCTCACACCTGTAATGCTAACACTTTGGGAGGCC TCAAGCTGAGGATTGCTTAAGCCCAGGAGCTTGAGGTTACAGTGAGCTATGATCATGCCA CTTCTAGATCTTGTCCAGGAGCTCTTGTATAGCTTCTGTTGAAATCTGTTGAACCAAACA TGATCCAGACACCAGAAGGAGGTGGGGAGGGAGGGAAAGGAAGATTAAAGAATAAATATG ACAAATGAGAAGTCTAAGAAGAGGATCTGGACTAAAGTGGCTGAAAGGATCCAGGTGCTG AACTGTACCCTCCTGAAGTCAAATAACACCCCCCACACCCATACTTTCTGGCCTGGCAGG ACCTTCTCTTATTGTAAAGTCTTTTGGAGTTAAGACCTCCCCAGACCCACTCAAAGTCCT CACCTCACTGTTCTTCTGCAGGAAGTCCAGAGCTATGATCTGGGTGACCTTGTCTCTTAA AAAAAAAAAAAAAAGCAGGCCGGGTGCAGTGGCTCGTGTCTGTAATCCCAGCACTTTGGG AGGATGAGGTGGGAGGATCACTTGAGGCCAGAAGTTTGAGAACAACCTGGGCAACATAGC AGGACCTCATCTCTACAAAAAATAAAAAAAAATTAGCCGGGCATGGTAGCACATGCCTGT AGTCCTAGCTACTCAGGAGGCTGAGGCAGGAGGACTGATTAAGCCCAGCAGGTGGAGGCA GTTGTGCCAATGCACTCCAGCCTGGGTGACAAAGTGAGATCCTGTCTCAAAGTAAAAACA AAACAAACAAACAAAAAAAAACAAAAAAGCAGATCCCTGTCCAGCAGATCCCTGGACAGA AATACTGATTCAGCAGCTGTGGAATGAGACCTAGAATCTATATTTTTTACATGGATCCAA GGTGATTCTGATGCTGGTGGGCTACAGACCACATTTTAAAAAGCACCGATTAAGAGTTAG TGACTTGCTCAAAGGCTCACAGCAGGAAGTACTAGCTTTGAATCCAGGATTCCTGCCTCC CAGACTGGTGCTGCTGCTGGATACATCTCACCAAAGCTGCCTCCTGAGCCTTGGTTTCTG CATTGTAAATGGAAATGGCAATTCCTTCCCCGCCTCCCTTCTTCATAGGCCCATTGTGAG GATAAAATGAGATAATGTAGGAGAAAGCACTTTTAAAAATGTAGAACTGGCAGCATTGTT AGCGATTATGCAAATACATGCAAATGAGTGCCGTGGGTGTGGCTGCTCACTTTGGGAGCC AGTGCTGGGATGTGGGTTTCAAAAGGTGGGTCGAGAAGGGAACTGGAAGAACTTTGATGA TGGGCATTGATCCCTGGGGAAAGTTTTGTAAAAAGGGCCGAATGAAGCAGAAGGCTGGGG TGGGAATCTGGGGGAGAGAGAGAACTATAGGCAGAAGAAGAGGCCTTCTTTCCTTTTTGG GTTTTATGTCACCAGATTTGAGGGTCCCTGGCTATGGGGACTGATCGGCAGAGGGAAGCC CCAGCTTGTGCCTGGGCACCAAAGGCAAAGCGTACCTCTTTGTTCTGTGATCTCTGGGCG GGGTACTCTGGGAGACACTGGCTCATAGCCCCTTTCCAGCTCATTTAGCTGGGAAAGCCT TTTATGATATATCTCGCCTCTATTCCTCCTCCCTAATGAAGCTGGAGCTGGGGCTGAGCT TTACTAAAATCATCCTCTTACTTGTTAAACAACCTGCTGTTTCCACATGGAGATGGTGCA GCAGGAAGGCTGAAAGTGAGATTTGAGGATAGCCAACCAAGGAGGCTGCAGTGCCGTCCT CCAACTTCTTTGCCACTTTCCCTTCTGTCCCATTTGCTCTCAGACGTGTCATCCAGGATT GCTAGGCCCTGAGGTGAGAACTGGCCTGTGATGCTTCCTGGGGCTGGCTATTTTGGGCAC CCCATTCCAAAGCTGCCGAGACCCCGGGATTCTAGAGCTACTTCTGTTCAGGAACGCCAT TGTTCTCCCTCCCCCGGCATCCCTGGGAATTGATGCTAATTTCAGCCTCTGATCCCTGAC TCATTCTCTTCTCCTCCCTGACTCATAGGGTGACCTTGGGTTTTTGAAGCCCCTCTCAGT GGGGAATTATGATGGCCACCATTTCAGCCCCAGATTGGTTTTAGGTGGGTGGGGCAGGGT GAGGGAAAGGAGAGAAAGGAATATTTAACTGCTTTCATTAAAATCACCATCTGAAGAGCT TTGTTTGCTTTGTGACTGCCTGGGCTGAACTCACCAGGCTTCTAAGAAGTCTCCCAGTTA ATCAACAAACCCCAGAATTCATAAGTGTAAAACATGAGGTGATTGTTCCTTCAGGCAAAA CATCCAGTGAATGAGATCCCTGGGCCCACCCCACCACTTTTATCCTGGAAGAAGCTTCAG TGGGGACAGAGGCAGGGGATGGGTACAGTAACTCTGTCAGAGGTTCTCTCTGGTGTAAGA CTGGAAAGGCAGGGGTTAACCCGGCTTTGTCCTGGTTGATGGATTCTGGAATCATAATCC ATTAGCTTTGCCTGCATGGAGAGAGGCCAGGCGAAAGCATTCAGATTTGTCTTTGTTCTG TGCTTTTGCCATGCCTGCCAGGCACAGAGGGGCTGTGGACACGTAACCCCCACCCCCCAC ACCATGACCAAGAGACAATGAAATACTCTTGGGGGCTATCTTGATTGCTATTGATCCCAA AGCCCTCTCCCATGGGGGAAATAAGCAGTTTCAGCTCTTGGTTATTCAGGCTATGAAACA GATCATCCTAAAAACATCACTCCAGGGGCTTGTACCTGCCTAATTCTGCTGGGCCCTGGC ATTTTAAACAAGACTAAGCACTGACTAAAGAGCGGGTTTCGAGAAGTCAGATGGTGGTGG GGATGGTGGAGTCAGGAAAACCTGGCATTAAACTTTGGGTGTAGATAAACTTAATACAGG CAGTGGCAATAGCCTGAGATTAAAAAAGAAACATTAGCTGCTATTATTATTAATGTTAGA ATGATTAACTATTTACAAAAGACTGAGGATGTTTCTGTAAAATGTACCTTATTAGGGAGT ATGCTGTTCTCATGATAAGGTAGCTGTGCCTAAGCAGCCTCTCTGTATCTGCTCCCTGCA GGCTGCGCTACATGGTGAAGCAGTTGGAGAATGGGGAGATAAACATTGAGGAGCTGAAGA AAAATCTGGAGTACACAGCTTCTCTGCTGGAAGCCGTCTACATAGATGAGACACGGTGAG AGAGACCGACAGACAGAGAAGGAGAAAGATGTCAGACATAGTGTTCCAGAGAGAGGGGTT AAGACAAAGATAGACACATGTGGCATGGACAGAGACCGGAAGAAAGAGAGAGGGTGGACC AGATATAAAGAGCTCTAGGTAGTGGCTCACACCTGTAATCCTAGCACTTTGGAGGCCAAG ATGGGTGGATTCTTTGAACCCAGGAGTTTGAGACCAGCCTGGGCAACATGGCAAGACCCT GTCTCTACAAAAAAAAAAAAATTAGCCAGGCATGGTGGCATGCTCCTGTAGTTCTAGCTA CTCGGGAGGCTGAGGTGGAAGGATGGCTTGAGCCCAGGAGGCAGAGGTTGCAGTGAGCTG AGATTGCGCTGCTGCACTCCAGCCTGGTGTGACAGAGCAAGACCCTGTCTCAAAATAAAT AAATAAATAAATAAATAAAAAAAATAAAAAAAGAGCTCCAGGTATCCAGGGAGAAATAGT GGTAAGAGATAAAGAAGCAGAGGCAGACATAGAGATGCAGAGATAGAGACAAACACAGAT ATCAAGAAGGACAGAAGACTGCTTCAGAGTTGGAAGGGACCTTAAAGCTCATCTATTCCA CTGTGGAATACCTCTAGATGTGTGCTGCCCAACATGGGAGCCACCATTCTGGGTGGCTAT TGAGCACCTCAAATGTGGCAAGTATGAACTGAGATGTGTACATAAAATACATGATGGATT TCAAAGACTTAGAAAAAAGAATGTAAGATATTCATATATATATATATATATTTTTTTGTT TTGAGACAGAGTTTACTCTTGTTGCCCAGGCTGAAGGGCAATGGTGTGATCTTGGCTCAC TGCAACCTCTGCCTCTGGGGTTCAAGCAATTCTTCTGCCTCAGCCTCCTGAGTAGCTGGA TTACAGGCATGTGCCACTACGCCCAGCTAATTTTTGTATTTTTAGTAGAGATGGGGTTTC TCCATGTTGGTCAGGCTGGTCTCGAACTCCTGACCTCAGGTGATCTGCCTGCCTTGGCCT CCCAAAGTCCTGGGGATTACAGGCGTGAGCTACCGCGCCCAGCCGATATCTCATTAATAT ATTTTATAAGGCTGGGCGTGATGGTTCATGCCTGTAATCCCAGCACTTTGGGAAGTTGAG GCAGCCTGATTGCTTGAGCCCAGGAATTCGAGACCAGCCTGGGCAACATGATGAAACCCT GTCTCTACAAAAAATAAGAATTAGCTGGGCATGGTGATGTGCATCTGTAGTCCCAGCTAC TTGGGAGGCTGAGGGGGGAGGATCACCTGAATCTGGGGAGGTTGAGGTTGCAGTGAGCTG TGATCACACCACTGCACTCCAGTCTGGGCGATAAAGTGAGACCCTGTCTAAAAATACACA CACACACACACACACACACACACACACACACACACACACGGTTTCATGTTGAAATGATAT TTTGGAGGTATTAGGTAAAATAAAATTTATTGCCGGGCACGGTGGCTCACGCCTATAATC CCAGCACTTTGGGAGGCTGAGGCGGATGGATCAACTGAGGTCAGGAATTCAAGACCAGCC TGGCGTGGTGGTAGGCACCTGTAATCCCAGCTACTCAGGAGGCTGAGGCAGGAGAATCGC TCGAACCCGGGAGGCGGAGGTTGCAGTGAGCCAAGATCGCGCCATTGCACTCCAGCCTGG GCAACGGAGTGAGACTCCATCTCAAAAAAAAAATTATCATTAAAGTCAATTTCACCTATT TCTCTTTTCCTTTTTAACGTGGCCTACTAGACAATTTAAAATTTCATATATGCGGCTTGC ATTTTATTTCTATTGGATGGTGCTGCTCTATAGCATCCCTGAAAGATGCGTTCCATTTCC TGCTTAAACACTTCCATAGTTGGGATGCTCACTACCTCACATGGAGACCTGTTTCATTAT TGGAGATGTTAGATAAAGAAATAAAAAGATATAGAGAAAGAAAGGAAACAGGGTTGAAGA CAGAGAGCTGGCATGAGAGTTACTAAATGTGGGGTATGGCTGGGTACAGGGTCTCTAGGC TGTGGAAGCACCTGCTGTCTTTCCTCTGTGACTCCCCTTCTGGGGTCTCAGGCAAATCTT GGACACGGAGGACGAGCTGCAGGAGCTGCGGTCAGATGCCGTGCCTTCGGAGGTGCGGGA CTGGCTGGCCTCCACCTTCACCCAGCAGGCCCGGGCCAAAGGCCGCCGAGCAGAGGAGAA GCCCAAGTTCCGAAGCATTGTGCACGCTGTGCAGGCTGGGATCTTCGTGGAACGGTGAGG CTCGCCCACACTCAGCCTCCCTCTGCCTTTAGCTGTGCCCCTCTTTCCCAGCCACCCTGG TCTTCCATGACCACCAGCCATATGATCCCATGGCTCATCCCCACATCCCCAGCTGGCCAC ACCTCCACTCCCAGACCTTCATATGTGGGCTTCTTCTCATTGTTCTCTCTCAGGATGTTC CGGAGAACATACACCTCTGTGGGCCCCACTTACTCTACTGCGGTTCTCAACTGTCTCAAG GTAATCTCTGGGTTTTTGGGAAAGAGGAGAAAGTTAGGGGATGGAATAGCCACTGGGACT TCTAGACCCTGTTTATGGCATTATTTTTGCCTTCCTTTTTTTTTTTTGAAATGGAGTCTC GCTCTTGTCACTCAGGCTGGAGTGCAGTGGCGTGATCTCGTCTCACTGCAACCTCTGCCT CCCTGCAAGCGATTCTCCTGCCTCAGCCTCCTGAGTAGCTGGGATTACAGGTGCCCACCA CCATGCCCAGCTAATTTTTGTAGTTTTAGTAGAGATGGGGTTTCACCATGTTGGCCAGGC TGGTCTCGAACTCTTGACCTCAAGTGTTCTGCCCACCTCGGTCTCCCAAAGTATTGGGAT TACAGACGTGAGCCACTGCGCCCGGCCTGCCTTCCCTTTTAACTGTTGTTCCCACATTTA TCAAAACTGCTTTTGCCCAGTATAGGAGCAAACTCCTGCCTTCCTGTCTCTCCCATACTG AGAGATATATGGGAAGAAAGAGGCACACTTTACCATTTCTTTGCTTTCCTATTTACCAAG ACTTTGTACTCATGGGAAGTCCTTCTTGAAGTCTAACTTCAACCCTTGCTGCTGCTGGAA AGCCACATAATCTATTGTTTCTCCATAGAACCTGGATCTCTGGTGCTTTGATGTCTTTTC CTTGAACCAGGCAGCAGATGACCATGCCCTGAGGACCATTGTTTTTGAGTTGCTGACTCG GCATAACCTCATCAGCCGCTTCAAGGTTGGGCAGCATCCTACCTCTACCTCCAGGCAGGA TTCTCCACTCCTCTCATGCCTGTTCTAAAAGCCTCCCAACAAACAGATTCCATAGATCCC CTCACTCAGTCTCAACATCAGGGAAGTCTCCCCATGCCCACGCCCAGCCTAGCCTTTCTT TCACTTGCTGCAGTCTTAGTTCCAGACTTCATTAATTGATTTCTAGGGGGAGATTCTCGG TCTGCAACCATCTAGCCTGGGATTCTGCTCTCTCCCGCTTTGCTTTTTTCCCCCAACTTG TCCTCTCTAGGCTGACTTGCAGTGTGGACACTGGAGGCCTGGAGTTCAGATGCTGTCAGC CAGTGCCCTTTGGGACTAGAAACCATGTTTCCTGGATAAAATTGGCCACTCCCTCCCCCG TCCCCCAGTTCTGGTCTCTGTGCAAGGAATTATATAGAGAAGGTCAGCTCTTGACAGGGC TCGGGGCGGGGGCTTGTATGACAGGGGGACGGTGTGTGAACTTCATTTGCTCTTCAGCTT GTCTGGATGGGAAGAATTATATGAGATTAAGTCCTTCCTAGATCCTGTACCAGGAGGGAG CATCTTTTGGGAGGGAAAAAGTGCCAGGAAAAAAACAAAACACTTTCACATGGACAAATC ACATTTGGAAGTAGAGGGTGAGGGAGGTTGAAGAGCCGTAATGGGGATATTGGGTCAGCA CTTTGGGGAGCAGTAGATGTTAAAGGTGAAGGGAAACGTGGATGATCTGAAGGGCCATAG AGAGGGGCGGTCAAAGGAGTCCAGGTGGAGGGTCCCCTCCCAGGCCGGCTTCGGGAGGTC ATTCCATCCATCCTCTGCCTCCACTTCACTAGAACAAATTATCTGTGCATGTAAGCCCTT CCTTCACCCTTGACTCCTCCTTTTACAACAACTCCCTAGGGAGTTTCCAAAACTTTCCTG AGATGCTCAGCTGAAATTTTCTTAAGTGCCTTCCGGAAGCCTGTTCTGCAATTTTACTTT CTTCTTTCCAATCCTGCCCTCTCCAGGACAGAGAATAGTAGGGCTCTCTTTTTCCTAAGA CTTTTCCCAGCTCATGTTTCCCCAAACTGGCTCTCAGACTTCAGTCACTAGATTCTCCTA AACTCTGCCTCCTTACCTGGAAGGACTGGGTCTGGGGGACCTCAAGAGTAGCTGTTTTGG GTTAGGTTTGGCCCAGTCCCAGTCTGCTTTGCTCCAAGGCAGTTAGAGGAAGGAGGGGGT GCTTCTTGTTTTAGTTTTCTCTGATGATAGGGCCAGCAGCAGCTGCCCTTCTCAAACTCC ACATTCTTTTCCTGGGCACCTAGCCCCTCCCCTACTCCTCCCTTTTTCTTCCCTTCCCTC CAGGGACGCCATGGCAACGCAAAAGCAAGGGCAGTTGTCATGGAAACAGTCCTTTAAAAT TTCCTGAATTTGGGGCACAGCCCTCCAGGGGTGCGGGTGGGGGATGTTAGGGTCTGACTG ACTAGTGGTGCTTCTTCTGTGTCTCTGTCACTATATTGCTCATCTCTACAGAAACCTCCC GAGTCCTGAACCTTCGTCCCCTCCTAGCCTCAAGAGATTCAGGGACAGATCACCAGTCCT GTCCTCTGGGAGCCTTGAGCCTTTTGAAGGAGGCAGACATACCCTAAGGGCGTACACAGA GACAGGGCCCGGATTCAGAGTAGCTGGACAGAGCTCTGGCTGCTGGTGCTTTTGTGTGTG TTCTGTGGGACTGAGGGCGCGGGTACTGGTGCATGTAGAGGGTAAGTGGTCAGGGAGGGC AACCCACATCTGGCTGGAAGAGTCCTCTCTAGGTCATCTTCTTCATTCCCTTACTTCCGA GCCCTTCTTCATGGTTTTGGATGTGGGGATGGAGTGGGATGTTTGGAAGGTAGGAGGGAA GCTTTCTTTCATTTTCTTTGAAATCTCCAGGGAAATAATAATAATTATAGCTATTCTTTA GAGAGCATTTACTAAATGCCTTGTACTTATCTCATTAATTTCCAGGTAGGTGGTATTATC TTTCATTCTGCAATTAAGTATCTGAGGCACAGAGAGGCATGTGACTTACCCAAGGTTGCA CAGCCAGCAGGTGGTAGAGGCAGGATATGAGCCAGGTTCACCTAACTAGGTTCTGTGCTC TCTCCCTATGCCACACTGCCTTCTAAAGAAAGTTGTTGATCTCGGTCCGTAATCACCACC ATTCCTGTGGATCCTTGATATATCTCCATTTCCCCTAACTCCCCGCAGATTCCCACTGTG TTTTTGATGAGTTTCCTGGATGCCTTGGAGACAGGCTATGGGAAGTACAAGAATCCTTAC CACAACCAGATCCACGCAGCCGATGTTACCCAGACAGTCCATTGCTTCTTGCTCCGCACA GGGATGGTGGTAGGTGCCCTGGAGATGATTCTTCTGTGATTCAGGGCCTATGGCTACAGA ACTGGGAGGTCTAGACTGTACTCCCATTTCCATTTCTCCTCGTTGGTTCTTCTTGGGCAC TCCAAAGCCTTGACAGAGCCAAACTGGATTAACTCACTCTAGAGAATTCCCAGGTAGACT AAAACTCGTTGGACAGTGCTAGGGACATGTGCTGGGATGCAGTGGGAGTGTTGCAGGTTC GGATGGAGGAAGGTCCTTGGCCATTTCAGGAGCTGAGAAACCTGGCTGCATTAACCAAGA GCTGGCCTGGAAGCATGGAAGGGATGGGATGAGTGATCTAGCCTGTGTGTGGAGGTTCCT GGGAAGTGACCAGCAGGCGTCACCCCTCTCTCATTCTTTCTCTTTCCTCCTGTAGCACTG CCTGTCGGAGATTGAGCTCCTGGCCATCATCTTTGCTGCAGCTATCCATGATTATGAGCA CACGGGCACTACCAACAGCTTCCACATCCAGACCAAGTGAGGGGTGGGGATGTGGCAGGG GCAGGAGGGGCCAAGAGGAGGTGGGGAGGTTGCCGGAGTCCCTCCTTACAGGGGGTGGTC ATGATGACCTTTGGCTTTGTAGGTCAGAATGTGCCATCGTGTACAATGATCGTTCAGTGC TGGAGAATCACCACATCAGCTCTGTTTTCCGATTGATGCAGGATGATGAGATGAACATTT TCATCAACCTCACCAAGGATGAGTTTGTGTGAGCAGAAGCCAGTACTTGGCATCCCTAAG AGACTCCCTTACCACAAACTCCATTTTCCACTTCCTGGACCTCCTGCCCAGCAGCGCTGA GGGGACTGATTGCTTCTCTTTTTATGTCCGCTCAGAGAACTCCGAGCCCTGGTCATTGAG ATGGTGTTGGCCACAGACATGTCCTGCCATTTCCAGCAAGTGAAGACCATGAAGACAGCC TTGCAACAGCTGGAGAGGTGGCATCTGGTGGGGTGTGGCTGGGGCCAGGCCAGAGGGAGG GGTGTGTGAACTGGGGGGGTATACACAAGGGTAGTTGGTGTGCCAGGTCTTTACCTCGCT GTAGAGACTCCACTGGCTTCAGGTATCAGACTGCATCTCTATGTGAGAGAGAGAGAGAGT GTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTCCTTACGTTTACTCACAGCC TTGGCAGCTGATCCACTGGAGAGTGCTTTGGGCTGGGAATCTAAGATGGGGGTTCTCATC GTAGCTCTGGGACAGGCTTACTCTGGAATGTTGGAAAATTCATTCAACCCTTCTGCCCCA GTTTTATTACCTCTGAAATGGTGAAAATGATACGCCTCCCCCCACAACAGCTTGCCCCTA GTTCCTAGTCTCATAGGGCTATTGGGAGAGTCATACGAGGTTTAAAAAAATGCATAGAAC AAATGCCATAATTACATCTAATGTTGCTTAGAAGTGAGTGGGAATGTATAAATGTGTGTG AGAGTGGACTGTGTGTGTGTGTGTCCTGAAGGTGTGTGTTAATCTCTGTGTAAGGTGTTT ATGTGTGGGATGCAGTGTCACAGCGGGTCATTGTTGAGGGTATAATAATAATTATTACTA TTCTAGATAATATCTACTGAGCACTTATTATGTGCTAGACACTCTCCTGAATACTTATTT GTTGTTTGTCACTTAATTCTCAGAACCACTCGATATGTGGTAGGGTTGTTATTTCCATTT TAGAGTTGAAGAAAATGAAATATGGAAATTTTAAGTAACTTGCTCAGTGTCACGCGGCTA ACATGTGGTAGGTATAGACGTGAACCCAGGCCCTTTGATTCTAAGAGCCTGGGCTCTCAG CTACTAACCCGTGCTGCTACCTAAACATATATAAGTGTGTGTGTGTCTGTGTGTGGGGTG TGTGTGTAGCTTTGGAGGGTGTTTGAAGTTATGTGAGGCCGGGCGTGGTGGCTCATGCCT ATAATTCCAGCACTTTGGGAGGCCGAGGCAGGTGGATAGCTTGAGGTCAGGAATTTGAGA CCAGCCTGGCCAACACGGTGAAACACTGTCTCTACCAAAAAAATACAAAAATTAGCTGGG TGTGGTGGCATGCACGCCTGTAGTCCCAGCTATTCGGGAGGCTGAGGTGGGAGAATCACT TGAACCCAGGTGACAGAGGTTGCAGTGAGCTGAGATTGTGCCACTGCACTCCAGCCCGGG CAACAGAGTGAGACCCTGTCTCAAAAAAAAAAAAAAAAAAAGGAAGAAGTTATGTGATAG GGTGTGCGTGGGAAGTTAGGGAATGGTCCTAACTTCCTTTTCCTAAAAGATCAGTCTCCC TTCCCTTGCCATCTGCCCCAACCAGGATTGACAAGCCCAAGGCCCTGTCTCTACTGCTCC ATGCTGCTGACATCAGCCACCCAACCAAGCAGTGGTTGGTCCACAGCCGTTGGACCAAGG CCCTCATGGAGGAATTCTTCCGTCAGGTAGCGTGGCATCTTTGCCTTCCCTGTGCCTATG GGGGCCTTCTCTCCCCTTTTGCCCTCCAAGTTCCCCAATCCTGTTCCACATCCTCCTTTT GCTACCTGTAGTCTCTGACCTGATCCCAAATCCTTGGGGTAAAACCCCATTATCCTAAAA GCCTAACAATAGTTGCATTTCATTTGCATATATTTCATTTGCATATTACTAATTTCCAGG TCAACAGTGCAGAAATTTCACACAACAACCCCCCACCCCCACCACTTGCCACCTGTACCC CAGATCTGGTAGGTCTGAGGTATCCTCTCCAGCTTTCCTACCCTGTTCCCTCCTCTAGGG TGACAAGGAGGCAGAGTTGGGCCTGCCCTTTTCTCCACTCTGTGACCGCACTTCCACTCT AGTGGCACAGTCTCAGATAGGTGAGTGTCCTCTCCTGCAGGAAGGGGAGGACTGGGAGGG GGAAAAGATGCTGCCTGGGTCAGGATTGCTCCAAGTCCTCAATCCCCCCAAACCATTCTT CCTGTAGAGGAAAGCCTACTGTGCTAGAGCATGGGGTCCTGGGTTAGGAGGCCAGGGGGC TGCAATGGCAGGAAGGAGCTCTCTGGGGCACCAAGACATCATCCCAAAGCCTGCCCTGCA TTGGGAAGTTTTCAGCCCCAGGTTACCTCTCCATCCTCTTTCATAAGCAGCCAGGGGTCC TGGCCATGCCAGCTGCATGCTCTGCCTAGCCCTCCAGATAATAGTAAGACATCTCTACGG CATTGCTCCTCCACTGCAGGGTTCATCGACTTCATTGTGGAGCCCACATTCTCTGTGCTG ACTGACGTGGCAGAGAAGAGTGTTCAGCCCCTGGCGGATGAGGACTCCAAGTCTAAAAAC CAGCCCAGGTGAGGGTGGCTGGGGTAGCCAGATATCTTGGTTCAGGAAGGCAGTGGTAGG GAGGGATTTGGACTCACAGAGAGGACCGACTCACAGCCATGGTGGGGTGGTGGGGAGGCA GACTGCTTCAAGCTTGGGAGTCCCTCTGCCGTCAGGGACAGAAGGATGGGATCAGAAGGG TGTGACCTGTACCTATGCTCCCCTTCACCATATTTTTGTTTCTTCCATTAGCTGTCTTTC TGCCTTCTGGCTAATCTTGTTTTAATTTTCCTTCTACCAGGAGGGAAGATGTGGAGAGGG AGGGGTGAAATGAGGGGGAGAGGGACAGGGACTTGGGGAATATCTAGTAGAGGAAAAGAG GAAGATGAAGTTCCCTGAACCTTCTCCTGGTCTTCCATGTCCTGCACTCCCAGGGCTAAG GTGGTTCTGGAGTGGGCTGGGGCTTACCTCTTGCGGCTTTTGGGGGTTCTGCTTCTAGCT TTCAGTGGCGCCAGCCCTCTCTGGATGTGGAAGTGGGAGACCCCAACCCTGATGTGGTCA GCTTTCGTTCCACCTGGGTCAAGCGCATTCAGGAGAATAAGCAGAAATGGAAGGAACGGG CAGCAAGTGGTGGGTACCATGGCAGAGGGCAGGGGTGAGAACTTGTGTGGGTGGATCATG GAGCACTAGGAGGTCCATTTTTCTTAAGCCCCTGGGGAAACCCTTTGCCGGACTCCTTGA TTTGGGAGTGGAGCTGATCAGACCAGTTAGATCACAGGAAAGACTGGCTGAGTGGCCTGG AATGTTCTAAGAATGGGGGCCGTAGAGATGATAGAGACAGTCAGATATTCCACAACCCAA GGGTCCCTGTGCACACTGTGGTCCCTGTAAATGGTGCCCCTGTAGATTTGGCTAATTTGG TGGCCCTGGCTGGGAAATCTCTTCCTGTGTGAGGGGGTGGTAGGGTGGTGTTGAGGGTTC TGAGTTTTAGCAAGGCTGGAGAGGCTCTTCCCAAGTGGGGATGGGTTGAATGTAGTTCAG CTTGAAGGCAGGTTGATGGATGAGAATCCCTTACATGTCTCCACATACTCCTTGGGTTCT GGGGAAGAATACTTCTTGGCCTAAGCTCAGCCTCCTTTATGCTCCTCTACAGGCATCACC AACCAGATGTCCATTGACGAGCTGTCCCCCTGTGAAGAAGAGGCCCCCCCATCCCCTGCC GAAGATGAACACAACCAGAATGGGAATCTGGATTAGCCCTGGGGCTGGCCCAGGTGAGCC TGTTGTGGTGGAGGGTGTAGGAGAGCTGGTGTCTATCATGGCATCTTTGTTGGGTCGTCT CTGGGCTCCAGTGGATGCGACATTCTCTCTCCCCTTTTGAGCAGTAAAATGGAGCGAGTG AAGACATAGAATGGAGCCAAAGTGTGGGTGGAGCAGGGAAATCCTCCCACGCTCTTCTGT CCCCCAGTCCCTGCAGGAACAAAGGAGGTACCTTCTCAGAACAGCAGCAGAACAGGGTGG GCCCATGCCAGGTGACAGCTAACCTGCACCGCACCTTAGGGAGGGTTAGGGAAAAGGAGC CCAGCCAGGGCACACAGCTCAGTGAGGGCAGCTGAACGTGACTTCGACTTCAGCCCCTAT TCACCCCCTTGGCTGGGCACCCTTCTGAAGGGCATTTTTTGCACAGCTCTACTCGGGACT GAGTGGGGATCAGGACTTGGAGAAGGAAGGTCAGGTTGGAGGTGAAGGCAAAGCTCAGGG CACTGAAGTTTCTCCCTCTTTCCCCAGGTCTTCATTGAGTCCAAAGTGTTTGATGTCATC AGCACCATCCATCAGGACTGGCTCCCCCATCTGCTCCAAGGGAGCGTGGTCGTGGAAGAA ACAACCCACCTGAAGGCCAAATGCCAGAGATTTGGGGTTGGGGAAAGGGCCCCTCCCCAC CTGACACCCACTGGGGTGCACTTTAATGTTCCGGCAGCAAGACTGGGGAACTTCAGGCTC CCAGTGGTCACTGTGCCCATCCCTCAGCCTCTGGATTCTCTTCATGGCCAGGTGGCTGCC AGGGAGCGGGGAGCTTCCTGGAGGCTTCCCAGGGCCTTGGGGAAGGGTCAGAGATGCCAG CCCCCTGGGACCTCCCCCATCCTTTTTGCCTCCAAGTTTCTAAGCAATACATTTTGGGGG TTCCCTCAGCCCCCCACCCCAGATCTTAGCTGGCAGGTCTGGGTGCCCCTTTTCCTCCCC TGGGAAGGGCTGGAATAGGATAGAAAGCTGGGGGTTTTCAGAGCCCTATGTGTGGGGAGG GGAGTGGATTCCTTCAGGGCATGGTACCTTTCTAGGACCTGGGAATGGGGTGGAGAGGAC ATCCTCTTCACCCCAGAATTGCGCTGCTTCAGCCCCATCTCCAGCCTGATCCTCTGAATC TTCCTTCCCTCCCTTTCTGATACAGTGACTGGGGCAAAAGGAGCCATTGTGACCAGGGGC TGCGGGAGGCCTTTCCTGGGACCTTCCTTGGGACTGGTCTGGGCCCCTGGGGCTTGTCGC CTGCCCTGAGTCCGGAGCCCTTTGCCTCCTTCCTCTCCCCTGGGGCTGGGAGGCTCCATC CGACCAATGTCTGTAAAGTGCTTTGAGGATCTCCCCAGCAAAGCACCTTCAGAATGTATC GACACCAGCTGGGTTAGGGTCAAGGGTGCCTGGGGAGGGTGAGTAATCCTGCATTGCTAA AAGAGAGGGTCTGTCCCCTCCTCTCCACGTCCCAGAACTGGCCCAGCTGCAGGCACTAAG AAGCTCCTCCCCTGAGACAAGTGAGGGGTAGTCGGTGAAAGGCAGATGGACAAGGGGCTC AGGGCTGCTGCCTTCCTGTCCTCTGGAGAGAACCCAGCCAGGCGCGGTGCCCCTTCCTCT CCTCAGGCTCCTCCTTGCCCCCACCTTGCCCCAGGAAAGGCCAAAGTCCAGGTGACTGCC CTCCTTCTTTCTTGTAAATACCAACCATGCATTTGTACAGTGGGCCCTGTTCATGCGAAA TCCACATCCATGGTCTCCTAGACCTGCTACCCTGGTACTTCCACCCTACCCCACCCCGAG AAGGGCAGAGACGCATGTGACTCACCCCTGCCCTTGGTTTCCCAGACCCCTGCTATAGCC AGAGAACAATAAAGAAGGGAGACCAGG OMIM ID 171891