Entrez gene ID | | 51582 |
Official gene symbol | | AZIN1 |
Full name | | antizyme inhibitor 1 |
Aliases | | ,MGC3832,MGC691,OAZI,OAZIN,ODC1L, |
Gene summary | | Ornithine decarboxylase (ODC) catalyzes the conversion of ornithine to putrescine in the first and apparently rate-limiting step in polyamine biosynthesis. Ornithine decarboxylase antizymes play a role in the regulation of polyamine synthesis by binding to and inhibiting ornithine decarboxylase. The protein encoded by this gene is highly similar to ODC. It binds to ODC antizyme and stabilizes ODC, thus inhibiting antizyme-mediated ODC degradation. Two alternatively spliced transcript variants have been found for this gene. [provided by RefSeq] |
Location | | Chromosome: 8 Locus: 8q22.3 |
Gene position | | 103876397 - 103838536 Map Viewer |
Gene orientation | | minus |
Gene size | | 37862 bp |
Gene sequence |
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OMIM ID | | 607909 |
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