Entrez gene ID | | 5163 |
Official gene symbol | | PDK1 |
Full name | | pyruvate dehydrogenase kinase, isozyme 1 |
Aliases | | ,-, |
Gene summary | | Pyruvate dehydrogenase (PDH) is a mitochondrial multienzyme complex that catalyzes the oxidative decarboxylation of pyruvate and is one of the major enzymes responsible for the regulation of homeostasis of carbohydrate fuels in mammals. The enzymatic activity is regulated by a phosphorylation/dephosphorylation cycle. Phosphorylation of PDH by a specific pyruvate dehydrogenase kinase (PDK) results in inactivation. [provided by RefSeq] |
Location | | Chromosome: 2 Locus: 2q31.1 |
Gene position | | 173420779 - 173463862 Map Viewer |
Gene orientation | | plus |
Gene size | | 43084 bp |
Gene sequence |
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