Entrez gene ID | | 51652 |
Official gene symbol | | CHMP3 |
Full name | | vacuolar protein sorting 24 homolog (S. cerevisiae) |
Aliases | | ,NEDF,VPS24, |
Gene summary | | This gene encodes a protein that sorts transmembrane proteins into lysosomes/vacuoles via the multivesicular body (MVB) pathway. This protein, along with other soluble coiled-coil containing proteins, forms part of the ESCRT-III protein complex that binds to the endosomal membrane and recruits additional cofactors for protein sorting into the MVB. This protein may also co-immunoprecipitate with a member of the IFG-binding protein superfamily. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream ring finger protein 103 (RNF103) gene. [provided by RefSeq] |
Location | | Chromosome: 2 Locus: 2p24.3-p24.1 |
Gene position | | 86790620 - 86730553 Map Viewer |
Gene orientation | | minus |
Gene size | | 60068 bp |
Gene sequence |
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OMIM ID | | 610052 |
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