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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for CHMP3 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID51652
Official gene symbolCHMP3
Full namevacuolar protein sorting 24 homolog (S. cerevisiae)
Aliases,NEDF,VPS24,
Gene summaryThis gene encodes a protein that sorts transmembrane proteins into lysosomes/vacuoles via the multivesicular body (MVB) pathway. This protein, along with other soluble coiled-coil containing proteins, forms part of the ESCRT-III protein complex that binds to the endosomal membrane and recruits additional cofactors for protein sorting into the MVB. This protein may also co-immunoprecipitate with a member of the IFG-binding protein superfamily. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream ring finger protein 103 (RNF103) gene. [provided by RefSeq]
LocationChromosome: 2   Locus: 2p24.3-p24.1
Gene position86790620 - 86730553  Map Viewer
Gene orientationminus
Gene size60068 bp
Gene sequence
OMIM ID610052