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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for ASB2 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID51676
Official gene symbolASB2
Full nameankyrin repeat and SOCS box-containing 2
Aliases,ASB-2,MGC40044,
Gene summaryThe protein encoded by this gene is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. They contain ankyrin repeat sequence and SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. This gene is induced by all-trans retinoic acid. In myeloid leukemia cells, the expression of this encoded protein has been shown to induce growth inhibition and chromatin condensation. Multiple alternatively spliced transcript variants have been described for this gene but their full length sequences are not known. [provided by RefSeq]
LocationChromosome: 14   Locus: 14q31-q32
Gene position94423767 - 94400513  Map Viewer
Gene orientationminus
Gene size23255 bp
Gene sequence
OMIM ID605759