Entrez gene ID | | 51699 |
Official gene symbol | | VPS29 |
Full name | | vacuolar protein sorting 29 homolog (S. cerevisiae) |
Aliases | | ,DC15,DC7,DKFZp564F0223,FLJ20492,PEP11, |
Gene summary | | This gene belongs to a group of vacuolar protein sorting (VPS) genes that, when functionally impaired, disrupt the efficient delivery of vacuolar hydrolases. The protein encoded by this gene is a component of a large multimeric complex, termed the retromer complex, which is involved in retrograde transport of proteins from endosomes to the trans-Golgi network. This VPS protein may be involved in the formation of the inner shell of the retromer coat for retrograde vesicles leaving the prevacuolar compartment. Alternative splice variants encoding different isoforms, and usage of multiple polyadenylation sites have been found for this gene. [provided by RefSeq] |
Location | | Chromosome: 12 Locus: 12q24 |
Gene position | | 110939916 - 110929330 Map Viewer |
Gene orientation | | minus |
Gene size | | 10587 bp |
Gene sequence |
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OMIM ID | | 606932 |
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