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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for PADI3 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID51702
Official gene symbolPADI3
Full namepeptidyl arginine deiminase, type III
Aliases,MGC126307,MGC126308,PAD3,PDI3,
Gene summaryThis gene encodes a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The family members have distinct substrate specificities and tissue-specific expression patterns. The type III enzyme modulates hair structural proteins, such as filaggrin in the hair follicle and trichohyalin in the inner root sheath, during hair follicle formation. Together with the type I enzyme, this enzyme may also play a role in terminal differentiation of the epidermis. This gene exists in a cluster with four other paralogous genes. [provided by RefSeq]
LocationChromosome: 1   Locus: 1p36.13
Gene position17575593 - 17610728  Map Viewer
Gene orientationplus
Gene size35136 bp
Gene sequence
OMIM ID606755