Database of mammalian genes
Home

Home Search Browse Statistics User guide FAQs Links Questions Contribute Download


Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for ACSL5 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID51703
Official gene symbolACSL5
Full nameacyl-CoA synthetase long-chain family member 5
Aliases,ACS2,ACS5,FACL5,
Gene summaryThe protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme is highly expressed in uterus and spleen, and in trace amounts in normal brain, but has markedly increased levels in malignant gliomas. This gene functions in mediating fatty acid-induced glioma cell growth. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq]
LocationChromosome: 10   Locus: 10q25.1-q25.2
Gene position114133916 - 114188138  Map Viewer
Gene orientationplus
Gene size54223 bp
Gene sequence
OMIM ID605677