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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for ERAP1 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID51752
Official gene symbolERAP1
Full nameendoplasmic reticulum aminopeptidase 1
Aliases,A-LAP,ALAP,APPILS,ARTS-1,ARTS1,ERAAP,ERAAP1,KIAA0525,PILS-AP,PILSAP,
Gene summaryThe protein encoded by this gene is an aminopeptidase involved in trimming HLA class I-binding precursors so that they can be presented on MHC class I molecules. The encoded protein acts as a monomer or as a heterodimer with ERAP2. This protein may also be involved in blood pressure regulation by inactivation of angiotensin II. Three transcript variants encoding two different isoforms have been found for this gene.
LocationChromosome: 5   Locus: 5q15
Gene position96143892 - 96096514  Map Viewer
Gene orientationminus
Gene size47379 bp
Gene sequence
OMIM ID606832