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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for PGGT1B (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID5229
Official gene symbolPGGT1B
Full nameprotein geranylgeranyltransferase type I, beta subunit
Aliases,BGGI,GGTI,
Gene summaryProtein geranylgeranyltransferase type I (GGTase-I) transfers a geranylgeranyl group to the cysteine residue of candidate proteins containing a C-terminal CAAX motif in which 'A' is an aliphatic amino acid and 'X' is leucine (summarized by Zhang et al., 1994 [PubMed 8106351]). The enzyme is composed of a 48-kD alpha subunit (FNTA; MIM 134635) and a 43-kD beta subunit, encoded by the PGGT1B gene. The FNTA gene encodes the alpha subunit for both GGTase-I and the related enzyme farnesyltransferase.[supplied by OMIM]
LocationChromosome: 5   Locus: 5q22.3
Gene position114598569 - 114546527  Map Viewer
Gene orientationminus
Gene size52043 bp
Gene sequence
OMIM ID602031