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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for SERPINB6 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID5269
Official gene symbolSERPINB6
Full nameserpin peptidase inhibitor, clade B (ovalbumin), member 6
Aliases,CAP,DKFZp686I04222,MGC111370,MSTP057,PI6,PTI,SPI3,
Gene summaryThe protein encoded by this gene is a member of the serpin (serine proteinase inhibitor) superfamily, and ovalbumin(ov)-serpin subfamily. It was originally discovered as a placental thrombin inhibitor. The mouse homolog was found to be expressed in the hair cells of the inner ear. Mutations in this gene are associated with nonsyndromic progressive hearing loss, suggesting that this serpin plays an important role in the inner ear in the protection against leakage of lysosomal content during stress, and that loss of this protection results in cell death and sensorineural hearing loss. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq]
LocationChromosome: 6   Locus: 6p25
Gene position2972090 - 2948393  Map Viewer
Gene orientationminus
Gene size23698 bp
Gene sequence
OMIM ID173321